• 9136 Citations
  • 47 h-Index
1981 …2020

Research output per year

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Research Output

2006

Regulation of the alpha-fetoprotein promoter: Ku binding and DNA spatial conformation

Liénard, P., De Mees, C., Drèze, P. L., Dieu, M., Dierick, J. F., Raes, M., Szpirer, J. & Szpirer, C., Oct 2006, In : Biochimie. 88, 10, p. 1409-1417 9 p.

Research output: Contribution to journalArticle

The importance of catch-up growth after early malnutrition for the programming of obesity

Bieswal, F., Ahn, M-T., Reusens, B., Holvoet, P., Raes, M., Rees, W. & Remacle, C., 2006, In : Obesity. 14, p. 1330-1343 14 p.

Research output: Contribution to journalArticle

The importance of catch-up growth after early malnutrition for the programming of obesity in male rat

Bieswal, F., Ahn, M. T., Reusens, B., Holvoet, P., Raes, M., Rees, W. D. & Remacle, C., Aug 2006, In : Obesity. 14, 8, p. 1330-1343 14 p.

Research output: Contribution to journalArticle

2005

Assessment of some tools for the characterization of the human osteoarthritic cartilage proteome

de Ceuninck, F., Marcheteau, E., Berger, S., Caliez, A., Dumont, V., Raes, M., Anract, P., Leclerc, G., Boutin, J. A. & Ferry, G., 1 Sep 2005, In : Journal of Biomolecular Techniques. 16, 3, p. 256-265 10 p.

Research output: Contribution to journalArticle

Hypoxia-inducible factor-1-dependent overexpression of myeloid cell factor-1 protects hypoxic cells against tert-butyl hydroperoxide-induced apoptosis

Piret, J-P., Minet, E., Cosse, J-P., Ninane, N., Debacq, C., Raes, M. & Michiels, C., 2005, In : Journal of Biological Chemistry. 280, 10, p. 9336-9344 9 p.

Research output: Contribution to journalArticle

Identification of membrane-associated proteins regulated by the arbuscular mycorrhizal symbiosis

Valot, B., Dieu, M., Recorbet, G., Raes, M., Gianinazzi, S. & Dumas-Gaudot, E., Nov 2005, In : Plant Molecular Biology. 59, 4, p. 565-580 16 p.

Research output: Contribution to journalArticle

Mitochondrial biogenesis in mtDNA-depleted cells involves a Ca 2+-dependent pathway and a reduced mitochondrial protein import

Mercy, L., De Pauw, A., Payen, L., Tejerina Vargas, S. V., Houbion, A., Demazy, C., Raes, M., Renard, P. & Arnould, T., Oct 2005, In : FEBS Journal. 272, 19, p. 5031-5055 25 p.

Research output: Contribution to journalArticle

Mitochondrial dysfunction induces triglyceride accumulation in 3T3-L1 cells: Role of fatty acid β-oxidation and glucose

Vankoningsloo, S., Piens, M., Lecocq, C., Gilson, A., De Pauw, A., Renard, P., Demazy, C., Houbion, A., Raes, M. & Arnould, T., 1 Jan 2005, In : Journal of Lipid Research. 46, 6, p. 1133-1149 17 p.

Research output: Contribution to journalArticle

Role for casein kinase 2 in the regulation of HIF-1 activity

Mottet, D., Ruys, S. P. D., Demazy, C., Raes, M. & Michiels, C., 10 Dec 2005, In : International Journal of Cancer. 117, 5, p. 764-774 11 p.

Research output: Contribution to journalArticle

Up-regulation of 94-kDa glucose-regulated protein by hypoxia-inducible factor-1 in human endothelial cells in response to hypoxia

Paris, S., Denis, H., Delaive, E., Dieu, M., Dumont, V., Ninane, N., Raes, M. & Michiels, C., 3 Jan 2005, In : FEBS Letters. 579, 1, p. 105-114 10 p.

Research output: Contribution to journalArticle

2004

Enhancement of transfection efficiency through rapid and noncovalent post-PEGylation of poly(dimethylaminoethyl methacrylate)/DNA complexes

Pirotton, S., Muller, C., Pantoustier, N., Botteman, F., Collinet, S., Grandfils, C., Dandrifosse, G., Degée, P., Dubois, P. & Raes, M., Aug 2004, In : Pharmaceutical Research. 21, 8, p. 1471-1479 9 p.

Research output: Contribution to journalArticle

Hypoxia and CoCl protect HepG2 cells against serum deprivation- and t-BHP-induced apoptosis: A possible anti-apoptotic role for HIF-1

Piret, J-P., Lecocq, C., Toffoli, S., Ninane, N., Raes, M. & Michiels, C., 2004, In : Experimental Cell Research. 295, 2, p. 340-349 10 p.

Research output: Contribution to journalArticle

Proteomics as a way to identify extra-radicular fungal proteins from Glomus intraradices - RiT-DNA carrot root mycorrhizas

Dumas-Gaudot, E., Valot, B., Bestel-Corre, G., Recorbet, G., St-Arnaud, M., Fontaine, B., Dieu, M., Raes, M., Saravanan, R. S. & Gianinazzi, S., 1 Jun 2004, In : FEMS Microbiology Ecology. 48, 3, p. 401-411 11 p.

Research output: Contribution to journalArticle

2003

Autotaxin is released from adipocytes, catalyzes lysophosphatidic acid synthesis, and activates preadipocyte proliferation. Up-regulated expression with adipocyte differentiation and obesity

Ferry, G., Tellier, E., Try, A., Grés, S., Naime, I., Simon, M. F., Rodriguez, M., Boucher, J., Tack, I., Gesta, S., Chomarat, P., Dieu, M., Raes, M., Galizzi, J. P., Valet, P., Boutin, J. A. & Saulnier-Blache, J. S., 16 May 2003, In : J. Biol Chem. 278, 20, p. 18162-18169 8 p.

Research output: Contribution to journalArticle

Impact of ageing on proteasome structure and function in human lymphocytes

Carrard, G., Dieu, M., Raes, M., Toussaint, O. & Friguet, B., 1 May 2003, In : The international journal of Biochemistry & Cell biology. 35, 5, p. 728-739 12 p.

Research output: Contribution to journalArticle

mtCLIC is up-regulated and maintains a mitochondrial membrane potential in mtDNA-depleted L929 cells.

Arnould, T., Mercy, L., Houbion, A., Vankoningsloo, S., Renard, P., Pascal, T., Ninane, N., Demazy, C. & Raes, M., 2003, In : The FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 17, 14, p. 2145-2147 3 p.

Research output: Contribution to journalArticle

Role of ERK and calcium in the hypoxia-induced activation of HIF-1

Mottet, D., Michel, G., Renard, P., Ninane, N., Raes, M. & Michiels, C., 2003, In : Journal of Cellular Physiology. 194, 1, p. 30-44 15 p.

Research output: Contribution to journalArticle

2002

Creb activation induced by mitochondrial dysfunction is a new signaling pathway that impairs cell proliferation

Arnould, T., Vankoningsloo, S., Renard, P., Houbion, A., Ninane, N., Demazy, C., Remacle, J. & Raes, M., 15 Jan 2002, In : The EMBO journal. 21, 1-2, p. 53-63 11 p.

Research output: Contribution to journalArticle

Effects of homocysteine on the cellular responses of murine endothelial cells cultured in vitro

Tacheny, A., Dos Santos Mendes, S., Huet, A. C., Van Steenbrugge, M., Michiels, C., Holvoet, P. & Raes, M., 2002, In : Annals of the New York academy of sciences. 973, p. 550-554 5 p.

Research output: Contribution to journalArticle

ERK and calcium in activation of HIF-1

Mottet, D., Michel, G., Renard, P., Ninane, N., Raes, M. & Michiels, C., 2002, In : Annals of the New York academy of sciences. 973, p. 448-453 6 p.

Research output: Contribution to journalArticle

Identification of 30 protein species involved in replicative senescence and stress-induced premature senescence

Dierick, J. F., Kalume, D. E., Wenders, F., Salmon, M., Dieu, M., Raes, M., Roepstorff, P. & Toussaint, O., 20 Nov 2002, In : FEBS Letters. 531, 3, p. 499-504 6 p.

Research output: Contribution to journalArticle

Identification of the phospholipase A2 isoforms that contribute to arachidonic acid release in hypoxic endothelial cells: Limits of phospholipase A2 inhibitors

Michiels, C., Renard, P., Bouaziz, N. O., Heck, N., Eliaers, F., Ninane, N., Quarck, R., Holvoet, P. & Raes, M., 15 Jan 2002, In : Biochemical Pharmacology. 63, 2, p. 321-332 12 p.

Research output: Contribution to journalArticle

Is HIF-1α a pro- or an anti-apoptotic protein?

Piret, J-P., Mottet, D., Raes, M. & Michiels, C., 2002, In : Biochemical Pharmacology. 64, 5-6, p. 889-892 4 p.

Research output: Contribution to journalArticle

Proteomics in experimental gerontology

Dierick, J. F., Dieu, M., Remacle, J., Raes, M., Roepstorff, P. & Toussaint, O., 2002, In : Experimental Gerontology. 37, 5, p. 721-734 14 p.

Research output: Contribution to journalArticle

Regulation of gene expression by oxygen: NF-κB and HIF-1, two extremes

Michiels, C., Minet, E., Mottet, D. & Raes, M., 1 Nov 2002, In : Free Radicals in Biology and Medicine. 33, 9, p. 1231-1242 12 p.

Research output: Contribution to journalArticle

Stress-induced premature senescence and replicative senescence are different phenotypes, proteomic evidence

Dierick, J. F., Eliaers, F., Remacle, J., Raes, M., Fey, S. J., Larsen, P. M. & Toussaint, O., 1 Sep 2002, In : Biochemical Pharmacology. 64, 5-6, p. 1011-1017 7 p.

Research output: Contribution to journalArticle

2001

Adenovirus-mediated gene transfer of human platelet-activating factor-acetylhydrolase prevents injury-induced neointima formation and reduces spontaneous atherosclerosis in apolipoprotein E-deficient mice

Quarck, R., De Geest, B., Stengel, D., Mertens, A., Lox, M., Theilmeier, G., Michiels, C., Raes, M., Bult, H., Collen, D., Van Veldhoven, P., Ninio, E. & Holvoet, P., 22 May 2001, In : Circulation. 103, 20, p. 2495-2500 6 p.

Research output: Contribution to journalArticle

c-JUN gene induction and AP-1 activity is regulated by a JNK-dependent pathway in hypoxic HepG2 cells

Minet, E., Michel, G., Mottet, D., Piret, J-P., Barbieux, A., Raes, M. & Michiels, C., 2001, In : Experimental Cell Research. 265, 1, p. 114-124 11 p.

Research output: Contribution to journalArticle

Development of a sensitive multi-well colorimetric assay for active NFκB

Renard, P., Ernest, I., Houbion, A., Art, M., Le Calvez, H., Raes, M. & Remacle, J., 15 Feb 2001, In : Nucleic Acids Research. 29, 4, p. 1-5 5 p.

Research output: Contribution to journalArticle

HIF-1 and AP-1 cooperate to increase gene expression in hypoxia: Role of MAP kinases

Michiels, C., Minet, E., Michel, G., Mottet, D., Piret, J-P. & Raes, M., 2001, In : IUBMB Life. 52, 1-2, p. 49-53 5 p.

Research output: Contribution to journalArticle

Is the effect of interleukin-1 on glutathione oxidation in cultured human fibroblasts involved in nuclear factor-κB activation?

Renard, P., Delaive, E., Van Steenbrugge, M., Remacle, J. & Raes, M., Apr 2001, In : Antioxidants and Redox Signaling. 3, 2, p. 329-340 12 p.

Research output: Contribution to journalArticle

Transduction pathways involved in hypoxia-inducible factor-1 phosphorylation and activation

Minet, E., Michel, G., Mottet, D., Raes, M. & Michiels, C., 2001, In : Free Radicals in Biology and Medicine. 31, 7, p. 847-855 9 p.

Research output: Contribution to journalArticle

2000

ERK activation upon hypoxia: involvement in HIF-1 activation

Minet, E., Arnould, T., Michel, G., Roland, I., Mottet, D., Raes, M., Remacle, J. & Michiels, C., 18 Feb 2000, In : FEBS Letters. 468, 1, p. 53-58 6 p.

Research output: Contribution to journalArticle

1999

Development of a serum free medium for a human diploid fibroblast cell line

Pirotton, S., Dewelle, J., Eliaers, F., Delforge, D. & Raes, M., 1999, Animal cell technology: products from cells, cells as products. Bernard, A., Griffiths, B., Noe, W. & Wurm, F. (eds.). Dordrecht: Kluwer academic, p. 191-193 3 p.

Research output: Contribution in Book/Catalog/Report/Conference proceedingChapter

Hypoxia-induced activation of HIF-1: Role of HIF-1α-Hsp90 interaction

Minet, E., Mottet, D., Michel, G., Roland, I., Raes, M., Remacle, J. & Michiels, C., 29 Oct 1999, In : FEBS Letters. 460, 2, p. 251-256 6 p.

Research output: Contribution to journalArticle

1998

Design of a synthetic adhesion protein by grafting RGD tailed cyclic peptides on bovine serum albumin

Delforge, D., Gillon, B., Art, M., Dewelle, J., Raes, M. & Remacle, J., 1998, In : Letters in peptide science. 5, 2-3, p. 87-91 5 p.

Research output: Contribution to journalArticle

La réponse des cellules aux stress : relation avec le processus de vieillissement et la pathologie

Translated title of the contribution: Cellular response to stress: Relationship with ageing and pathologyToussaint, O., Raes, M., Michiels, C. & Remacle, J., May 1998, In : Médecine sciences : M/S. 14, 5, p. 622-635 14 p.

Research output: Contribution to journalArticle

1997

Effects of antioxidant enzyme modulations on interleukin-1-induced nuclear factor kappa B activation

Renard, P., Zachary, M. D., Bougelet, C., Mirault, M. E., Haegeman, G., Remacle, J. & Raes, M., 24 Jan 1997, In : Biochemical Pharmacology. 53, 2, p. 149-160 12 p.

Research output: Contribution to journalArticle

1996

Automated solid-phase synthesis of cyclic peptides bearing a side-chain tail designed for subsequent chemical grafting

Delforge, D., Art, M., Gillon, B., Dieu, M., Delaive, E., Raes, M. & Remacle, J., 15 Nov 1996, In : Analytical biochemistry. 242, 2, p. 180-186 7 p.

Research output: Contribution to journalArticle

Solid-phase synthesis of tailed cyclic peptides: the use of α-allyl-protected aspartic acid leads to aspartimide and tetramethylguanidinium formation

Delforge, D., Dieu, M., Delaive, E., Art, M., Gillon, B., Devreese, B., Raes, M., Van Beeumen, J. & Remacle, J., 1996, In : International Journal of Peptide Research and Therapeutics. 3, 2, p. 89-97 9 p.

Research output: Contribution to journalArticle

1995

Cellular aging and the importance of energetic factors

Toussaint, O., Michiels, C., Raes, M. & Remacle, J., 1995, In : Experimental Gerontology. 30, 1, p. 1-22 22 p.

Research output: Contribution to journalArticle

Differential regulation by cAMP of PDGF-induced p42(MAPK) and AP-1 activation in human lung fibroblasts.

Burton, M., Fernemont, I., Van Steenbrugge, M., Remacle, J. & Raes, M., 1995, In : Cell Biology International. 19, 8, p. 720-721 2 p.

Research output: Contribution to journalArticle

Inhibitory effects of cyclic AMP and prostaglandin E2 on PDGF-induced human lung fibroblast proliferation

Burton, M., Gillon, B., Eliaers, F., Remacle, J. & Raes, M., 1995, In : Journal of Experimental and Clinical Cancer Research. 14, 1 SUPPL., p. 180-181 2 p.

Research output: Contribution to journalArticle