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Research Output

Reinvestigation of the Branimycin Stereochemistry at Position 17-C

Čikoš, A., Triballeau, N., Hubbard, P. A., Žiher, D., Stouten, P. F. W., Doyon, J. G. P. O., Deschrijver, T., Wouters, J., Lépine, R. H. M. & Saniere, L., 19 Feb 2016, In : Organic Letters. 18, 4, p. 780-783 4 p.

Research output: Contribution to journalArticle

Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenase

Pilotte, L., Larrieu, P., Stroobant, V., Colau, D., Dolušić, E., Frédérick, R., De Plaen, E., Uyttenhove, C., Wouters, J., Masereel, B. & Van Den Eynde, B. J., 14 Feb 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 7, p. 2497-2502 6 p.

Research output: Contribution to journalArticle

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Reversal of Tumoral Immune Resistance by Inhibition of Tryptophan 2,3-Dioxygenase (TDO): Design, Synthesis and Preclinical Evaluation of a Novel TDO Inhibitor.

Dolušić, E., Larrieu, P., Moineaux, L., Stroobant, V., Pilotte, L., Colaux, D., Van den Eynde, B., Masereel, B., Wouters, J. & Frédérick, R., 2012, In : ChemMedChem. p. 371 1 p.

Research output: Contribution to journalLiterature review

Reversible inhibition of type B monoamine oxidase. Theoretical study of model diazo heterocylic compounds

Wouters, J., Ooms, F., Jegham, S., Koenig, J. J., George, P. & Durant, F., 1 Sep 1997, In : European Journal of Medicinal Chemistry. 32, 9, p. 721-730 10 p.

Research output: Contribution to journalArticle

Secondary nucleation study of sucrose crystallization: Experiments and modelling

Ouiazzane, S., Messnaoui, B., Wouters, J. & Bounahmidi, T., 1 Jan 2007, p. 467-473. 7 p.

Research output: Contribution to conferencePaper

Secondary structure of monoamine oxidase by FTIR spectroscopy

Wouters, J., Ramsay, R., Goormaghtig, E., Ruysschaert, J. M., Brasseur, R. & Durant, F., 21 Apr 1995, In : Biochemical and Biophysical Research Communications. 208, 2, p. 773-778 6 p.

Research output: Contribution to journalArticle

Selective Recognition of Phosphatidylcholine Lipids by a Biomimetic Calix[6]tube Receptor

Moerkerke, S., Wouters, J. & Jabin, I., 10 Aug 2015, In : Journal of Organic Chemistry. 80, 17, p. 8720-8726 7 p.

Research output: Contribution to journalArticle

Selective recognition of quaternary ammonium ions and zwitterions by using a biomimetic bis-calix[6]arene-based receptor

Moerkerke, S., Malytskyi, V., Marcélis, L., Wouters, J. & Jabin, I., 2017, In : Organic and Biomolecular Chemistry. 15, 42, p. 8967-8974 8 p.

Research output: Contribution to journalArticle

Selective recognition of small hydrogen bond acceptors by a calix[6]arene-based molecular container

Lavendomme, R., Desroches, F., Moerkerke, S., Topić, F., Wouters, J., Rissanen, K., Luhmer, M. & Jabin, I., 2 Jan 2020, In : Supramolecular Chemistry. 32, 1, p. 23-29 7 p.

Research output: Contribution to journalArticle

Sequential acid/base-catalyzed polycyclization of tryptamine derivatives. A rapid access to Büchi's ketone

Heureux, N., Wouters, J. & Markó, I. E., 10 Nov 2005, In : Organic Letters. 7, 23, p. 5245-5248 4 p.

Research output: Contribution to journalArticle

Short, asymmetric synthesis of epi-morphine ACNO analogues

Heureux, N., Wouters, J., Norberg, B. & Markó, I. E., 25 Oct 2006, In : Organic and Biomolecular Chemistry. 4, 21, p. 3898-3900 3 p.

Research output: Contribution to journalArticle

Small molecule crystallography in drug design

Wouters, J. & Ooms, F., 21 May 2001, In : Current Pharmaceutical Design. 7, 7, p. 529-545 17 p.

Research output: Contribution to journalArticle

Solid-state investigation on a new dimorphic substituted N-salicylidene compound: Insights into its thermochromic behaviour

Carletta, A., Dubois, J., Tilborg, A. & Wouters, J., 14 May 2015, In : CrystEngComm. 17, 18, p. 3509-3518 10 p.

Research output: Contribution to journalArticle

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Solid-state-trapped reactive ammonium carbamate self-derivative salts of prolinamide

Tilborg, A., Lanners, S., Norberg, B. & Wouters, J., 1 Dec 2013, In : ChemistryOPEN. 2, 5-6, p. 194-199 6 p.

Research output: Contribution to journalArticle

Species distribution and coordination of uranyl chloro complexes in acetonitrile

Hennig, C., Servaes, K., Nockemann, P., Van Hecke, K., Van Meervelt, L., Wouters, J., Fluyt, L., Görller-Walrand, C. & Van Deun, R., 21 Apr 2008, In : Inorganic Chemistry. 47, 8, p. 2987-2993 7 p.

Research output: Contribution to journalArticle

Stepwise hydration of protonated proline

Michaux, C., Wouters, J., Perpète, E. A. & Jacquemin, D., 3 Jul 2008, In : Journal of physical chemistry B. 112, 26, p. 7702-7705 4 p.

Research output: Contribution to journalArticle

Stereoselective synthesis of boat-locked glycosides designed as glycosyl hydrolase conformational probes

Thiery, E., Reniers, J., Wouters, J. & Vincent, S. P., 2015, In : European Journal of Organic Chemistry. 2015, 7, p. 1472-1484 13 p.

Research output: Contribution to journalArticle

Stereospecific Winding of Polycyclic Aromatic Hydrocarbons into Trinacria Propellers

Mosca, D., Stopin, A., Wouters, J., Demitri, N. & Bonifazi, D., 2 Nov 2017, In : Chemistry - A European Journal. 23, 61, p. 15348-15354 7 p.

Research output: Contribution to journalArticle

Open Access
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Structural Analysis of d -Phenylglycinamide Salts Uncovers Potential Pitfalls in Chiral Resolution via Diastereomeric Salt Formation

Tumanova, N., Seiler, V., Tumanov, N., Robeyns, K., Filinchuk, Y., Wouters, J. & Leyssens, T., 3 Jul 2019, In : Crystal Growth & Design. 19, 7, p. 3652-3659 8 p.

Research output: Contribution to journalArticle

Open Access

Structural analysis of pyrrolidinones

Camus, F., Norberg, B., Legrand, A., Rigo, B., Durant, F. & Wouters, J., 1 Feb 2000, In : Acta crystallographica Section C: Crystal Structure communications. 56, 2, p. 193-196 4 p.

Research output: Contribution to journalArticle

Structural analysis of some bis-(8-isopropyl-isoquinolinium) derivatives reveals a preferential folded conformation leading to a stereoselective attack by sodium borohydride

Dilly, S., Badarau, E., Dufour, F., Nistor, I., Hubert, P., Seutin, V., Wouters, J. & Liégeois, J. F., 25 Sep 2014, In : Journal of molecular structure. 1074, p. 435-440 6 p.

Research output: Contribution to journalArticle

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Structural and enzymatic study of tryptophan 2,3-dioxgenase (TDO), a potential target in anticancer immunotherapy.

Moineaux, L., Charlier, C., Dolušić, E., Larrieu, P., Pilotte, L., Colaux, D., Stroobant, V., Galleni, M., Masereel, B., Van den Eynde, B., Wouters, J. & Frédérick, R., 2010, In : Drugs of the future. 35, suppl A, p. 189

Research output: Contribution to journalLiterature review

Structural and enzymatic study of tryptophan 2.3-dioxygenase (TDO), a potential target in anticancer immunotherapy

Moineaux, L., Charlier, C., Dolusic, E., Larrieu, P., Pilotte, L., Colau, D., Stroobant, V., Galleni, M., Masereel, B., Van den Eynde, B., Wouters, J. & Frédérick, R., 2010, p. PC.355, 21st ISMC, Brussels, Belgium, September 5-9, 2010, Drugs of the Future, volume 35, issue suppl. A, pp. 217-218. 2 p.

Research output: Contribution to conferencePaper

Structural and theoretical studies of [6-bromo-1-(4-fluorophenylmethyl)-4(1H)-quinolinon-3-yl)]-4-hydroxy-2-oxo-3-butenoïc acid as HIV-1 integrase inhibitor

Vandurm, P., Cauvin, C., Guiguen, A., Georges, B., Van, K. L., Martinelli, V., Cardona, C., Mbemba, G., Mouscadet, J. F., Hevesi, L., Lint, C. V. & Wouters, J., 15 Aug 2009, In : Bioorganic & Medicinal Chemistry Letters. 19, 16, p. 4806-4809 4 p.

Research output: Contribution to journalArticle

Structural and theoretical study of 5-(R)-(methoxymethyl)-3-aryl-oxazolidin-2-ones, reversible monoamine oxidase inhibitors

Wouters, J., Moureau, F., Dory, M., Evrard, G., Koenig, J. J., Ducrey, F., Jarreau, F. X. & Durant, F., 1993, Trends in QSAR and molecular modelling 92. Wermuth, C. G. (ed.). Leiden: ESCOM, p. 291-293 3 p.

Research output: Contribution in Book/Catalog/Report/Conference proceedingChapter

Structural approach of human MAO-A using fold recognition (threading) techniques

Wouters, J., Depiereux, E. & Durant, F., 26 Sep 2000, In : Neurobiology. 8, 1, p. 119-128 10 p.

Research output: Contribution to journalArticle

Structural approach of the mechanism of inhibition of α-chymotrypsin by coumarins

Wouters, J., Huygens, M., Pochet, L., Pirotte, B., Durant, F. & Masereel, B., 8 Apr 2002, In : Bioorganic and medicinal chemistry letters. 12, 7, p. 1109-1112 4 p.

Research output: Contribution to journalArticle

Structural aspects of monoamine oxidase and its reversible inhibition

Wouters, J., 5 May 1998, In : Current Medicinal Chemistry. 5, 2, p. 137-162 26 p.

Research output: Contribution to journalArticle

Open Access
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Structural insight into cocrystallization with zwitterionic co-formers: Cocrystals of S-naproxen

Tumanova, N., Tumanov, N., Robeyns, K., Filinchuk, Y., Wouters, J. & Leyssens, T., 21 Sep 2014, In : CrystEngComm. 16, 35, p. 8185-8196 12 p.

Research output: Contribution to journalArticle

Structural insights into human 5-lipoxygenase inhibition: Combined ligand-based and target-based approach

Charlier, C., Hénichart, J. P., Durant, F. & Wouters, J., 12 Jan 2006, In : Journal of Medicinal Chemistry. 49, 1, p. 186-195 10 p.

Research output: Contribution to journalArticle

Structural insights into the acidophilic pH adaptation of a novel endo-1,4-β-xylanase from Scytalidium acidophilum

Michaux, C., Pouyez, J., Mayard, A., Vandurm, P., Housen, I. & Wouters, J., 1 Oct 2010, In : Biochimie. 92, 10, p. 1407-1415 9 p.

Research output: Contribution to journalArticle

Structural Investigation of Substituent Effect on Hydrogen Bonding in (S)-Phenylglycine Amide Benzaldimines

George, F., Norberg, B., Wouters, J. & Leyssens, T., 5 Aug 2015, In : Crystal Growth and Design. 15, 8, p. 4005-4019 15 p.

Research output: Contribution to journalArticle

Structural role for Tyr-104 in Escherichia coli isopentenyl-diphosphate isomerase: Site-directed mutagenesis, enzymology, and protein crystallography

De Ruyck, J., Durisotti, V., Oudjama, Y. & Wouters, J., 30 Jun 2006, In : Journal of Biological Chemistry. 281, 26, p. 17864-17869 6 p.

Research output: Contribution to journalArticle

Open Access
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Structure and function prediction of the Brucella abortus P39 protein by comparative modeling with marginal sequence similarities

De Fays, K., Tibor, A., Lambert, C., Vinals, C., Denoël, P., De Bolle, X., Wouters, J., Letesson, J. J. & Depiereux, E., 15 Apr 1999, In : Protein Engineering. 12, 3, p. 217-223 7 p.

Research output: Contribution to journalArticle

Structure and mechanism of action of isopentenylpyrophosphate-dimethylallylpyrophosphate isomerase

Wouters, J., Oudjama, Y., Ghosh, S., Stalon, V., Droogmans, L. & Oldfield, E., 19 Mar 2003, In : Journal of the American Chemical Society. 125, 11, p. 3198-3199 2 p.

Research output: Contribution to journalArticle

Structure and X-ray conformation of pseudodesmins A and B, two new cyclic lipodepsipeptides from Pseudomonas bacteria

Sinnaeve, D., Michaux, C., Van hemel, J., Vandenkerckhove, J., Peys, E., Borremans, F. A. M., Sas, B., Wouters, J. & Martins, J. C., 23 May 2009, In : Tetrahedron. 65, 21, p. 4173-4181 9 p.

Research output: Contribution to journalArticle

Structure of Thermus thermophilus type 2 isopentenyl diphosphate isomerase inferred from crystallography and molecular dynamics

De Ruyck, J., Rothman, S. C., Poulter, C. D. & Wouters, J., 23 Dec 2005, In : Biochemical and Biophysical Research Communications. 338, 3, p. 1515-1518 4 p.

Research output: Contribution to journalArticle