Projects per year
- 1 - 50 out of 90 results
Search results
-
Active
Mechanochemical deracemization: a sustainable approach to enantiopure compounds
Leyssens, T. (PI) & Wouters, J. (PI)
1/01/25 → 31/12/28
Project: Research
-
Targeted covalent probes to interfere with homomeric proteinprotein interactions: inhibition of lactate dehydrogenase (LDH) through covalent modification of key amino acids
Garcia Llinas, X. (PI), Pochet, L. (Supervisor) & Wouters, J. (CoI)
1/10/24 → 30/09/26
Project: Research
-
Identification of cellular regulators and pharmacological inhibitors of endophilin-A3 to manipulate unconventional endocytosis
Thines, L. (PI), Renard, H. F. (Supervisor) & Wouters, J. (CoI)
1/10/24 → 30/09/27
Project: Research
-
Crystallization in capsules under microfluidic control for the fundamental study of nucleation processes
Wouters, J. (PI) & SCHEID, B. (CoPI)
1/01/24 → 31/12/27
Project: Research
-
Plan national pour la reprise et la résilience: Plateforme de recherche pour la transition énergétique
Yans, J. (PI), Wouters, J. (PI), Lucas, S. (PI), Cecchet, F. (PI), Colomer, J.-F. (PI), Aprile, C. (PI), Berionni, G. (PI), Houssiau, L. (PI), Louette, P. (PI) & Su, B. L. (PI)
1/01/22 → 31/12/25
Project: Research
-
Télévie: Design and enzymatic evaluation of new inhibitors of the serine metabolic pathway as potential anticancer agents : structural and functional approach of PHDGH
Wouters, J. (Supervisor) & THEMANS, Q. (Researcher)
1/10/15 → …
Project: PHD
-
PERGAMENUM21: A trans-disciplinary study of parchment: Conservation issues, historical aspects and material prospects for the 21st century
Deparis, O. (PI), Nieus, J.-F. (CoI), Hermand, X. (CoI), Renard, E. (CoI), Wouters, J. (CoI), Debacq-Chainiaux, F. (CoI), Hespel, B. (CoI), d'Udekem d'Acoz Gevers, M. (CoI), Van Hoorebeeck, C. (CoI) & Charles, C. (CoI)
1/01/14 → …
Project: Research
-
Structural study of membrane protein TMEM45A, involved in the resistance of cancer cells against chemotherapeutic agents
DAL MASO, T. (PI) & Wouters, J. (Supervisor)
1/10/12 → …
Project: PHD
-
Euroscreen: Service agreement Euroscreen
KRIEF, A. (PI) & Wouters, J. (PI)
25/02/04 → …
Project: Research
-
Not started
Conception, synthèse caractérisation physico-chimique et biologique de dérivés de l'harmine substitués par un groupement 2-méthylpyridine comme composés antiprolifératifs
MARX, S. (Researcher), Wouters, J. (Supervisor) & MEINGUET, C. (PI)
Project: Research
-
Finished
Targeted covalent probes to interfere with homomeric proteinprotein interactions: inhibition of Mycobacterium tuberculosis serine phosphatase through covalent modification of key amino acids
Garcia Llinas, X. (PI), Pochet, L. (Supervisor) & Wouters, J. (CoI)
1/10/22 → 30/09/24
Project: Research
-
Metal complexes of calixarenes
Reynaud, O. (PI), Jabin, I. (PI), Wouters, J. (PI), Leherte, L. (Researcher), Nyssen, N. (Researcher) & Giraud, N. (Researcher)
15/06/22 → 30/10/23
Project: Research
-
Ultrahigh resolution crystal structures: chirality and non-covalent bonding in multicomponent crystal systems and pyramidal Lewis acids
Wouters, J. (PI), Berionni, G. (CoPI) & Leyssens, T. (CoPI)
1/01/22 → 31/12/23
Project: Research
-
Towards the design of innovating inhibitors for the first step of the kynurenine pathway
Mirgaux, M. (PI) & Wouters, J. (Supervisor)
1/10/21 → 30/09/23
Project: Research
-
Structural study of Lactate Dehydrogenase, a target for the design of new anticancer agents
Van Gysel, M. (PI) & Wouters, J. (Supervisor)
1/10/20 → 30/09/22
Project: Research
-
Structural study of the regulatory ACT domains of M.tuberculosis and B.melitensis phosphoserinephosphatases towards the design of selective inhibitors
Pierson, E. (PI) & Wouters, J. (Supervisor)
1/10/20 → 30/09/22
Project: Research
-
Preparation and physico-chemical characterization of (ionic) cocrystals of aryl hydantoins based on hydrogen, halogen, and chalcogen bonds
Wouters, J. (PI), Leyssens, T. (CoI) & Bodart, L. (Researcher)
1/01/20 → 31/12/23
Project: Research
-
Cocrystals as an alternative to combination drugs: cocrystallization, physico-chemical characterization and structural determination of cocrystallized active pharmaceutical ingredients
Bodart, L. (PI) & Wouters, J. (Supervisor)
1/10/19 → 30/09/21
Project: Research
-
Cancer immunotherapy and dual IDO/TDO inhibitors: design, synthesis, physico-chemical and biological characterizations
Mirgaux, M. (PI) & Wouters, J. (Supervisor)
1/10/19 → 30/09/21
Project: Research
-
FSR-Cofin : Design, synthesis and biological evaluation of E3-ligase ligands as therapeutic options (FSR part)
Wouters, J. (Supervisor) & Mambourg, K. (PI)
17/07/19 → 16/01/21
Project: Research
-
Study of lipase structures through MD simulations
Labar, G. (PI), Wouters, J. (PI) & Leherte, L. (PI)
22/02/19 → 31/12/21
Project: Research
-
Structural approach of M.tuberculosis phosphoserine phosphatase as drug target for the design of original inhibitors
Pierson, E. (PI) & Wouters, J. (Supervisor)
1/10/18 → 30/09/19
Project: Research
-
Development of inhibitors of LDHB tetramerizatuion to block oxidative lactate metabolism and signaling in cancer
Sonveaux, P. (PI), Frédérick, R. (CoI), Wouters, J. (CoI) & Piel, G. (CoI)
1/10/18 → 30/09/20
Project: Research
-
Cryo- and photo-crystallography of thermo- and photochromism in the solidstate: Photo/Thermo-CoXal approach
CARLETTA, A. (PI) & Wouters, J. (Supervisor)
1/10/18 → 30/09/20
Project: Research
-
Structural study of membrane proteins involved in chemoresistance of cancer cells
DAL MASO, T. (PI) & Wouters, J. (Supervisor)
1/01/18 → 30/09/19
Project: Research
-
Cocrystals as an alternative to combination drugs: cocrystallization, physico-chemical characterization and structural determination of cocrystallized active pharmaceutical ingredients
Bodart, L. (PI) & Wouters, J. (Supervisor)
1/10/17 → 26/09/19
Project: Research
-
Understanding regulation mechanisms involving G-quadruplexes by crystallisation of a complex between a G-quadruplex and a protein.
DE RACHE, A. (PI) & Wouters, J. (Supervisor)
1/10/17 → 30/09/20
Project: Research
-
Pow(d)er XRD: Crystal structure determination through high-resolution powder diffraction
Wouters, J. (PI) & Tumanov, N. (PI)
1/01/17 → 31/12/18
Project: Research
-
Etude structurale de protéines membranaires impliquées dans le cancer
RONDELET, G. (Researcher), DAL MASO, T. (Researcher) & Wouters, J. (PI)
1/01/17 → 30/09/19
Project: Research
-
Cryo- and photo-crystallography of thermo- and photochromism in the solid-state
Wouters, J. (Supervisor) & CARLETTA, A. (PI)
1/10/16 → 30/09/18
Project: Research
-
Structural and inhibition study of SerB2 (Mycobacterium tuberculosis phosphoserine phosphatase)
Haufroid, M. (Researcher) & Wouters, J. (Supervisor)
1/09/16 → 31/08/22
Project: PHD
-
Improving photochromism and thermochromism in the solid state by co- crystallization: an integrated physico-chemical investigation
Wouters, J. (PI)
1/01/16 → 30/12/17
Project: Research
-
Télévie: Design and enzymatic evaluation of new inhibitors of the serin metabolic pathway as potential anticancer agents : structural and functional approach of PHDGH and PSAT1.
Wouters, J. (Supervisor)
1/10/15 → 30/09/17
Project: Research
-
Télévie: Inhibition of DNA methylation: structural and functional study of the PWWP regulatory domains of DNMT 3A and B.
Wouters, J. (PI)
1/10/15 → 30/09/17
Project: Research
-
Télévie: Identification of chemosensitizing compounds inhibiting the resistance of taxol induced by TMEM45A protein on MDA-MB-231 cell line
Wouters, J. (Supervisor), Michiels, C. (Co-supervisor) & MARX, S. (Researcher)
1/10/15 → 30/09/19
Project: Research
-
ARC 15/20-068: Improving the Photochromism and Thermochromism in the Solid State by Co-crystallization : an Integrated Physico-chemical Approach
Champagne, B. (PI), Wouters, J. (PI) & Leyssens, T. (PI)
1/09/15 → 31/12/20
Project: Research
-
Régulation de l’homéostasie du cuivre au cours des différentes étapes du développement de 3 alpha-protéobactéries
Matroule, J.-Y. (PI), GILLET, S. (Researcher), Devos, D. (CoI) & Wouters, J. (CoI)
1/10/14 → 30/09/18
Project: PHD
-
Crystallographic study of the mechanisms of inhibition of IDO and TDO enzymes through protein engineering: help in the design of mixed inhibitors as potential anticancer agents.
THEMANS, Q. (PI) & Wouters, J. (Supervisor)
1/09/14 → 30/09/15
Project: Research
-
Télévie: Targeting methylation as therapy for adult T cell leukemia/lymphoma
Wouters, J. (PI)
1/10/13 → 30/09/15
Project: Research
-
La chiralité et les co-cristaux
Wouters, J. (CoI) & Leyssens, T. (PI)
1/07/13 → 30/06/17
Project: Research
-
-
synthèse et évaluation de dérivés de l'harmine
Wouters, J. (PI) & Masereel, B. (CoI)
1/10/11 → 30/09/13
Project: Research
-
Mechanistical study of Type 2 Isopentenyl Diphosphate Isomerase as a potential drug target.
DE RUYCK, J. (Researcher) & Wouters, J. (CoI)
1/10/11 → 30/09/14
Project: Research
-
Solid state synthesis of compounds of pharmaceutical interest
Dubois, J. (PI) & Wouters, J. (CoI)
1/09/11 → 31/08/17
Project: PHD
-
Télévie: Synthesis and evaluation of analogs of harmine as potential inhibitors of DYRK1A : pro-apoptotic compounds in melanoma and gliome models
Wouters, J. (PI) & Masereel, B. (CoI)
1/01/11 → 31/12/14
Project: Research
-
-
Synthèse, caractérisation physico-chimique, évaluations biologique et pharmaceutique de dérivés de l’harmine en tant qu’anticancéreux
MEINGUET, C. (PI) & Wouters, J. (CoI)
1/10/10 → 31/10/15
Project: PHD
-
Etude de l’inhibition de la 1-déoxy-D-xylulose-5-phosphate réductoisomérase (DXR)
POUYEZ, J. (PI) & Wouters, J. (CoI)
1/09/10 → 31/08/15
Project: PHD
-
Etude de dérivés beta-carbolines et 5H-indéno(1,2-c)pyridazine-5-ones en tant que modulateurs du métabolisme des monoamines: étude de l'inhibition des monoamines oxydases (MAOs)
Wouters, J. (PI) & Reniers, J. (Researcher)
1/09/10 → 30/09/12
Project: PHD