Design and synthesis of indolamine dioxygenase (IDO) for the treatment of cancer

Project: Research

Description

This project is a drug discovery program aimed at finding new chemical entities capable of inhibiting the immunosuppression mediated by indoleamine 2,3-dioxygenase (IDO) expression in tumors. The project also encompasses a phase I/II clinical trial with a first-generation IDO inhibitor, and a diagnostic application leading to the development of new diagnostic test for detecting IDO-positive cancers.
AcronymCANTOL
StatusFinished
Effective start/end date1/04/0831/03/12

Keywords

  • molecular design
  • medicinal chemistry
  • enzymology