Research output per year
Research output per year
Project Details
Description
This project is a drug discovery program aimed at finding new chemical entities capable of inhibiting the immunosuppression mediated by indoleamine 2,3-dioxygenase (IDO) expression in tumors. The project also encompasses a phase I/II clinical trial with a first-generation IDO inhibitor, and a diagnostic application leading to the development of new diagnostic test for detecting IDO-positive cancers.
| Acronym | CANTOL |
|---|---|
| Status | Finished |
| Effective start/end date | 1/04/08 → 31/03/12 |
Keywords
- molecular design
- medicinal chemistry
- enzymology
Funder and research program
- Wallonia: Competitive Clusters
Fingerprint
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
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Indoleamine 2,3-dioxygenase inhibitors: a patent review (2008-2012)
Dolušić, E. & Frédérick, R., 1 Oct 2013, In: Expert opinion on therapeutic targets. 23, 10, p. 1367-1381 15 p.Research output: Contribution to journal › Literature review › peer-review
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Indoleamine 2,3-Dioxygenase Inhibitory Activity of Derivatives of Marine Alkaloid Tsitsikammamine A
Dolušić, E., Larrieu, P., Meinguet, C., Colette, D., Rives, A., Blanc, S., Ferain, T., Pilotte, L., Stroobant, V., Wouters, J., Van Den Eynde, B., Masereel, B., Delfourne, E. & Frédérick, R., 1 Jan 2013, In: Bioorganic & Medicinal Chemistry Letters. 23, 1, p. 47-54 8 p.Research output: Contribution to journal › Article › peer-review
3 Downloads (Pure) -
Convenient one-pot formation of highly functionalized 5-halothiazoles
Dolusic, E., Modaffari, S., Pochet, L., Wouters, J., Masereel, B. & Frédérick, R., 1 Jul 2012, p. Book of Abstracts, Balticum Organicum Syntheticum, July 1-4 2012, Tallinn, Estonia, PO27, p. 74. 1 p.Research output: Contribution to conference › Poster
Open AccessFile75 Downloads (Pure)
Activities
- 7 Participation in conference
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Balticum Organicum Syntheticum 2012
Dolusic, E. (Poster)
1 Jul 2012Activity: Participating in or organising an event types › Participation in conference
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15th SIGMA-ALDRICH Organic Synthesis Meeting
Dolusic, E. (Poster)
1 Dec 2011 → 2 Dec 2011Activity: Participating in or organising an event types › Participation in conference
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47th RICT: Drug Discovery and Selection.
Dolusic, E. (Poster)
6 Jul 2011 → 8 Jul 2011Activity: Participating in or organising an event types › Participation in conference