Research Output

2020

Assessment of low plasma concentrations of apixaban in the periprocedural setting

Lessire, S., Dincq, A-S., Siriez, R., Pochet, L., Sennesael, A-L., Vornicu, O., Hardy, M., Deceuninck, O., Douxfils, J. & Mullier, F., 1 Aug 2020, In : International Journal of Laboratory Hematology. 42, 4, p. 394-402 9 p.

Research output: Contribution to journalArticle

Il faut rappeler que le 'risque zéro' n’existe pas: chronique 3 - covid-19

Flohimont, V., DOGNE, J-M. & FAUVILLE, MARIE-ALINE. (ed.), 4 May 2020, HR Square.

Research output: Book/Report/JournalCommissioned report

Open Access
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Inter-laboratory variability of the standardized ETP-based APC resistance assay (PB0386)

Morimont, L., Maloteau, V., Devel, P., Dogné, J-M., Bouvy, C. & Douxfils, J., 12 Jul 2020.

Research output: Contribution to conferencePoster

File
2019

Andexanet alfa for the reversal of factor Xa inhibitors

Favresse, J., Hardy, M., van Dievoet, M. A., Sennesael, A. L., Douxfils, J., Samama, C. M., Vornicu, O., Dincq, A. S., Lessire, S. & Mullier, F., 4 May 2019, In : Expert Opinion on Biological Therapy. 19, 5, p. 387-397 11 p.

Research output: Contribution to journalArticle

An update on laboratory assessment for direct oral anticoagulants (DOACs)

Gosselin, R. C., Adcock, D. M. & Douxfils, J., 1 May 2019, In : International Journal of Laboratory Hematology. 41, S1, p. 33-39 7 p.

Research output: Contribution to journalReview article

A Simple and Efficient Mechanochemical Route for the Synthesis of Salophen Ligands and of the Corresponding Zn, Ni, and Pd Complexes

Fusaro, L., Carletta, A., Dubois, J., Tumanov, N., Aprile, C., Wouters, J., Dalla Cort, A. & Leoni, L., 1 Jan 2019, In : Molecules. 24, 12, p. 2314 11 p., 2314.

Research output: Contribution to journalArticle

Open Access
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Assessment of second and third generation oral contraceptives APC resistance by a newly validated ETP-based APC resistance assay: a pilot study

Morimont, L., Evrard, J., Delvigne, A-S., Bouvy, C., Dogné, J-M. & Douxfils, J., Nov 2019, BSTH, 27th annual meeting, Program and Abstracts book, 28-29 november, 2019. p. 20 P04

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Assessment of the analytical performances and sample stability on ST Genesia system using the STG-DrugScreen application

Douxfils, J., Morimont, L., Bouvy, C., de Saint-Hubert, M., Devalet, B., Devroye, C., Dincq, A-S., Dogné, J-M., Guldenpfennig, M., Baudar, J., Larock, A-S., Lessire, S. & Mullier, F., Aug 2019, In : Journal of thrombosis and haemostasis : JTH. 17, 8, p. 1273-1287 15 p.

Research output: Contribution to journalArticle

Assessment of thrombomodulin resistance in women using second generation, third generation and progestin-only contraceptives

Morimont, L., Evrard, J., Delvigne, A-S., Bouvy, C., Dogné, J-M. & Douxfils, J., Nov 2019, BSTH, 27th annual meeting, Program and Abstracts book, 28-29 november, 2019. p. 20 P05

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Comparison of the impact of DOACs on hemostasis diagnostic tests

Siriez, R., Evrard, J., Dogne, J-M., Mullier, F. & Douxfils, J., 2019, Comparison of the impact of DOACs on hemostasis diagnostic tests.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

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Open Access

Determinants of the Quality of Warfarin Control after Venous Thromboembolism and Validation of the SAMe-TT2-R2 Score: An Analysis of Hokusai-VTE

Barco, S., Granziera, S., Coppens, M., Douxfils, J., Nijkeuter, M., Riva, N., Vanassche, T., Zhang, G., Lin, M., Kamphuisen, P. W., Cohen, A. T. & Beyer-Westendorf, J., 1 Jan 2019, In : Thrombosis and Haemostasis. 119, 4, p. 675-684 10 p.

Research output: Contribution to journalArticle

File

Identifying, Characterizing, and Understanding Nefiracetam in Its Solid State Forms: A Potential Antidementia Drug

Buol, X., Robeyns, K., Tumanov, N., Wouters, J. & Leyssens, T., 1 Nov 2019, In : Journal of Pharmaceutical Sciences. 108, 11, p. 3616-3622 7 p.

Research output: Contribution to journalArticle

8 Downloads (Pure)

Interaction of POPC, DPPC, and POPE with the μ opioid receptor: A coarse-grained molecular dynamics study

Angladon, M-A., Fossépré, M., Leherte, L. & Vercauteren, D., 1 Mar 2019, In : PLoS ONE. 14, 3, p. e0213646 19 p., e0213646.

Research output: Contribution to journalArticle

Open Access

Investigation of Cyclic Ligand Inhibiting CD2-CD58 Interactions Using Molecular Dynamics and Molecular Docking Approaches - COMP579

Vercauteren, D., Leherte, L., Laurent, A. & Jacquemin, D., Apr 2019, Abstracts of the 2557th Annual Meeting and Exposition of the American Chemical Society.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

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METHOD FOR DIAGNOSING HAEMOSTASIS DISORDERS USING ACTIVATED CHARCOAL

Douxfils, J., Gheldof, D. & Dogné, J-M., 15 Aug 2019, IPC No. G01N 33/ 86 A I, Patent No. WO2019154853, Priority date 6 Feb 2018, Priority No. EP20180155295

Research output: Patent

Molecular Recognition of Strong Acids by Using a 2-Ureido-4-Ferrocenyl Pyrimidine Receptor

Keszei, S. J., Balogh, S., Fehér, C., Nagy, L., Tumanov, N., Wouters, J., Lendvay, G. & Skoda-Földes, R., 17 Oct 2019, In : European Journal of Inorganic Chemistry. 2019, 38, p. 4095-4104 10 p.

Research output: Contribution to journalArticle

Open Access

New Insights into Photochromic Properties of N-Salicylideneaniline Derivatives Using a Cocrystal Engineering Approach

Mercier, G. M., Robeyns, K., Tumanov, N., Champagne, B., Wouters, J. & Leyssens, T., 2 Oct 2019, In : Crystal Growth & Design. 19, 10, p. 5544-5556 13 p.

Research output: Contribution to journalArticle

Open Access

Periodic DFT Study of the Effects of Co‐Crystallization on a N‐Salicylideneaniline Molecular Switch

Quertinmont, J., Leyssens, T., Wouters, J. & Champagne, B., 2 Oct 2019, ChemPhysChem, 20, 19, p. 2434-2442 1 p.

Research output: Contribution to specialist publicationArticle

Open Access

Proposition of a new scale for the harmonization and normalization of the nAPCsr: a scientific and regulatory need for clinical studies comparison

Morimont, L., Evrard, J., Delvigne, A-S., Bouvy, C., Dogné, J-M. & Douxfils, J., Nov 2019, BSTH, 27th annual meeting, Program and Abstracts book, 28-29 november, 2019. p. 20-21 P07

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

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Regio‐and Diastereoselective Functionalization of 3‐Amino‐hexahydrooxazoninones

Schurgers, B., Wouters, J., De Blieck, A., Van Lommen, G., Menet, C. & Verniest, G., 10 Jan 2019, In : European Journal of Organic Chemistry. 2019, 1, p. 36-40 5 p.

Research output: Contribution to journalArticle

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Structural Analysis of d -Phenylglycinamide Salts Uncovers Potential Pitfalls in Chiral Resolution via Diastereomeric Salt Formation

Tumanova, N., Seiler, V., Tumanov, N., Robeyns, K., Filinchuk, Y., Wouters, J. & Leyssens, T., 3 Jul 2019, In : Crystal Growth & Design. 19, 7, p. 3652-3659 8 p.

Research output: Contribution to journalArticle

Open Access
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Targeting the serine pathway: a promising approach against tuberculosis?

Haufroid, M. & Wouters, J., 1 Jun 2019, In : Pharmaceuticals. 12, 2, 66.

Research output: Contribution to journalArticle

Open Access
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Validation of an original ETP-based APC resistance assay for the evaluation of prothrombotic states

Morimont, L., Evrard, J., Delvigne, A-S., Bouvy, C., Dogné, J-M. & Douxfils, J., Nov 2019, BSTH, 27th annual meeting, Program and Abstracts book, 28-29 november, 2019. p. 20 P06

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

2018

1-(2-Hydroxybenzoyl)-thiosemicarbazides are promising antimicrobial agents targeting D-alanine-D-alanine ligase in bacterio

Ameryckx, A., Thabault, L., Pochet, L., Leimanis, S., Poupaert, J., Wouters, J., Joris, B., Van Bambeke, F. & Frederick, R., 5 Nov 2018, In : European journal of medicinal chemistry / Chimica therapeutica. 159, 5, p. 324-338 15 p.

Research output: Contribution to journalArticle

Open Access

Alternative Solid Forms: Co-crystals

Wouters, J., Braga, D., Grepioni, F., Aerts, L. & Quéré, L., 2018, Polymorphism in the Pharmaceutical Industry : Solid Forms and Drug Development. Hilfiker, R. & von Raumer, M. (eds.). Wiley, 32 p.

Research output: Contribution in Book/Catalog/Report/Conference proceedingChapter

Applications of Leveling Methods to Properties of Small Molecules and Protein Systems

Leherte, L., 2018, Innovations in Computational Chemistry: Theoretical and Quantum Chemistry at the Dawn of the 21st Century. Carbó-Dorca, R. & Chakraborty, T. (eds.). p. 197-248 51 p.

Research output: Contribution in Book/Catalog/Report/Conference proceedingChapter

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