Student theses

Analytical and clinical validation of sensitive assays for the diagnosis of immune heparin-induced thrombocytopenia

Author: Minet, V., 2017

Supervisor: Dogne, J. (Supervisor), Mullier, F. (External person) (Co-Supervisor), Laloy, J. (Jury), Lucas, S. (Jury), Masereel, B. (Jury), Chatelain, M. (External person) (Jury), Hoylaerts, M. F. (External person) (Jury) & Tardy, B. (External person) (Jury)

Student thesis: Doc typesDoctor of Biomedical and Pharmaceutical Sciences

Approche structurale et fonctionnelle de la première enzyme de la voie de la sérine: PHGDH, une cible potentielle pour le traitement du cancer

Author: Themans, Q., 18 Oct 2019

Supervisor: Wouters, J. (Supervisor), Leherte, L. (President), Unterlass, J. (External person) (Jury), Sirigu, S. (External person) (Jury) & Röhrig, U. (External person) (Jury)

Student thesis: Doc typesDoctor of Sciences

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Characterization of the anticancer properties of hydroxamate-based histone deacetylase inhibitors

Author: Lernoux, M., 22 Nov 2019

Supervisor: Schnekenburger, M. (External person) (Supervisor), DIEDERICH, M. (External person) (Co-Supervisor), Michiels, C. (Co-Supervisor), Arnould, T. (President), Sonveaux, P. (External person) (Jury), Wouters, J. (Jury), Gillet, J. (Jury) & Dicato, M. (External person) (Jury)

Student thesis: Doc typesDoctor of Biomedical and Pharmaceutical Sciences

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Conception, synthèse, caractérisation, évaluation pharmacologique et études in vivo de dérivés de l'harmine en tant que nouvelles molécules aux propriétés anticancéreuses.

Author: Meinguet, C., 25 Sep 2015

Supervisor: Wouters, J. (Supervisor), Vercauteren, D. (President), Masereel, B. (Jury), Lanners, S. (Jury), Willand, N. (External person) (Jury) & Mathieu, V. (External person) (Jury)

Student thesis: Doc typesDoctor of Sciences

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Conception de composés anti-cancéreux ciblant le domaine PWWP des DNMT3A et DNMT3B

Author: Themans, Q., 2014

Supervisor: Wouters, J. (Supervisor)

Student thesis: Master typesMaster in Chemistry

Design, synthesis and evaluation of coagulation FXIIa inhibitors as potential antithrombotic agents

Author: Bouckaert, C., 16 May 2017

Supervisor: Pochet, L. (Supervisor), Dogne, J. (Co-Supervisor), Lanners, S. (President), De Tullio, P. (External person) (Jury), Chatelain, C. (External person) (Jury) & TEN CATE, H. (External person) (Jury)

Student thesis: Doc typesDoctor of Biomedical and Pharmaceutical Sciences

Development of new debenzylative cyclization reactions & de novo synthesis of difluorinated glycomimetics

Author: Delbrouck, J., 20 Nov 2018

Supervisor: Vincent, S. (Supervisor), Lanners, S. (President), Berionni, G. (Jury), Singleton, M. S. (External person) (Jury) & Sollogoud, M. (External person) (Jury)

Student thesis: Doc typesDoctor of Sciences

Elaboration of quantum chemistry approaches for the simulation and the interpretation of vibrational Sum Frequency Generation signatures of functionalized surfaces

Author: Tetsassi Feugmo, C. G., 29 Nov 2018

Supervisor: Caudano, Y. (Co-Supervisor), Champagne, B. (Co-Supervisor), Liégeois, V. (President), Vercauteren, D. (Jury), Cecchet, F. (Jury), Guthmuller, J. (External person) (Jury) & Busson, B. (External person) (Jury)

Student thesis: Doc typesDoctor of Sciences

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Étude de la formation et des propriétés dynamiques, conformationelles et énergétiques d'assemblages supramoléculaires à base de nanotubes organiques et d'agrégats d'argent dans des brins d'ADN

Author: Staelens, N., 26 May 2014

Supervisor: Vercauteren, D. (Supervisor), Leherte, L. (President), Champagne, B. (Jury), Bonifazi, D. (Jury) & Laaksonen, A. (External person) (Jury)

Student thesis: Doc typesDoctor of Sciences

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Etude de la structure et de l'inhibition de la phosphosérine phosphatase de Mycobacterium avium

Author: Callaerts, N., Jun 2019

Supervisor: Wouters, J. (Supervisor)

Student thesis: Master typesMaster in Chemistry Professional focus

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Etude structurale d'imines et de phtalimides obtenus pas mécanosynthèse

Author: Dubois, J., 24 Nov 2017

Supervisor: Wouters, J. (Supervisor), Vercauteren, D. (President), Lanners, S. (Jury), Leyssens, T. (External person) (Jury), Robeyns, K. (External person) (Jury) & Tumanov, N. (Jury)

Student thesis: Doc typesDoctor of Sciences

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Etude structurale du domaine PWWP des DNMT3A et DNMT3B

Author: Dal Maso, T., 2015

Supervisor: Wouters, J. (Supervisor)

Student thesis: Master typesMaster in Chemistry

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Evaluation of thrombotic and/or bleeding risks associated with anticoagulotherapy.

Author: Douxfils, J., 24 Oct 2015

Supervisor: Dogne, J. (Supervisor), Mullier, F. (Supervisor), Masereel, B. (President), Chatelain, B. (Jury), Chatelain, C. (External person) (Jury), Verhamme, P. (External person) (Jury), TEN CATE, H. (External person) (Jury) & Ageno, W. (External person) (Jury)

Student thesis: Doc typesDoctor of Biomedical and Pharmaceutical Sciences

Influence des lipides de la membrane plasmique sur la structure et la fonction du récepteur opioïde µ par dynamique moléculaire gros grains

Author: Angladon, M., 1 Jul 2019

Supervisor: Vercauteren, D. (Supervisor), Wouters, J. (President), Michiels, C. (Jury), Leherte, L. (Jury), Kerff, F. (External person) (Jury) & Prévost, M. (External person) (Jury)

Student thesis: Doc typesDoctor of Sciences

Photochromic multicomponent crystalline materials based on N-salicylideneanilines

Author: Carletta, A., 13 Sep 2019

Supervisor: Wouters, J. (Supervisor), Leherte, L. (President), Champagne, B. (Jury), Leyssens, T. (External person) (Jury) & Roscini, C. (External person) (Jury)

Student thesis: Doc typesDoctor of Sciences

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Roles of extracellular vesicles and their microRNA cargo in chemotherapeutic resistance, pro-coagulant phenotype and as potential biomarkers in diffuse large B-cell lymphoma

Author: Bouvy, C., 16 Oct 2017

Supervisor: Dogne, J. (Supervisor), Chatelain, C. (Co-Supervisor), Caron, N. (President), Graux, C. (Jury), Michiels, C. (Jury), Stamatopoulos, B. (External person) (Jury) & Struman, I. (External person) (Jury)

Student thesis: Doc typesDoctor of Biomedical and Pharmaceutical Sciences

Structural study of non-nucleoside inhibitors of DNA (cytosine-5) methyltransferases

Author: Rondelet, G., 13 Dec 2016

Supervisor: Wouters, J. (Supervisor), Vercauteren, D. (President), Charlier, P. (External person) (Jury), WILLEMS, L. (External person) (Jury), De Bolle, X. (Jury) & Lanners, S. (Jury)

Student thesis: Doc typesDoctor of Sciences

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Study of the potential role of extracellular vesicles in thrombosis associated with paroxysmal nocturnal hemoglobinuria and red blood cell concentrates transfusions

Author: Wannez, A., 12 Sep 2018

Supervisor: Dogne, J. (Supervisor), Mullier, F. (Supervisor), Masereel, B. (President), Brichard, S. (External person) (President), Chatelain, C. (External person) (Jury), Chatelain, B. (Jury), Van Den Neste, E. (External person) (Jury), Delettre, F. (External person) (Jury) & Gerotziafas , G. (External person) (Jury)

Student thesis: Doc typesDoctor of Biomedical and Pharmaceutical Sciences

Synthèse de gamma-lactones et gamma-lactames beta-substituées en flux continu

Author: Collin, S., 4 Jun 2018

Supervisor: Lanners, S. (Supervisor), Vercauteren, D. (President), Pasau, P. (Jury), STEVENS, C. (External person) (Jury) & Lecomte-Norrant, E. (External person) (Jury)

Student thesis: Doc typesDoctor of Sciences

Synthesis and applications of novel fullerenes and silsesquioxanes based structures

Author: Cinà, V., 21 Feb 2020

Supervisor: Aprile, C. (Supervisor), Giacalone, F. (External person) (Co-Supervisor), Wouters, J. (Jury), Gruttadauria, M. (External person) (Jury) & Barattucci, A. (External person) (Jury)

Student thesis: Doc typesDoctor of Sciences

Synthesis of Heptose Mono- and Bisphosphate Analogues as Modulators of the Bacterial Innate Immunity and Inhibitors of the Bacterial Lipopolysaccharide

Author: Liang, L., 24 Oct 2019

Supervisor: Vincent, S. (Supervisor), Wouters, J. (President), Lanners, S. (Jury), BALLET, S. (External person) (Jury) & Biot, C. (External person) (Jury)

Student thesis: Doc typesDoctor of Sciences

Towards the total synthesis of L-783,277

Author: Hoang, T. V., 29 Jan 2016

Supervisor: Lanners, S. (Supervisor), Vercauteren, D. (President), Vincent, S. (Jury), Tzschucke, C. (External person) (Jury) & Hanquet, G. (External person) (Jury)

Student thesis: Doc typesDoctor of Sciences

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Vers la synthèse totale de la momilactone A

Author: Pirenne, V., 2014

Supervisor: Lanners, S. (Jury)

Student thesis: Master typesMaster in Chemistry