Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Dive into the research topics where Manon Mirgaux is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Collaborations and top research areas from the last five years
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Projects
- 2 Finished
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Towards the design of innovating inhibitors for the first step of the kynurenine pathway
Mirgaux, M. (PI) & Wouters, J. (Supervisor)
1/10/21 → 30/09/23
Project: Research
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Cancer immunotherapy and dual IDO/TDO inhibitors: design, synthesis, physico-chemical and biological characterizations
Mirgaux, M. (PI) & Wouters, J. (Supervisor)
1/10/19 → 30/09/21
Project: Research
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Domain architecture of the Mycobacterium tuberculosis MabR (Rv2242), a member of the PucR transcription factor family
Megalizzi, V., Tanina, A., Grosse, C., Mirgaux, M., Legrand, P., Dias Mirandela, G., Wohlkönig, A., Bifani, P. & Wintjens, R., 30 Nov 2024, In: Heliyon. 10, 22, e40494.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Downloads (Pure) -
Human indoleamine-2,3-dioxygenase 2 cofactor lability and low substrate affinity explained by homology modeling, molecular dynamics and molecular docking
Mirgaux, M., Leherte, L. & Wouters, J., 2023, In: Journal of Biomolecular Structure & Dynamics. 42, 9, p. 4475-4488 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile51 Downloads (Pure) -
Structural study of bioisosteric derivatives of 5-(1 H-indol-3-yl)-benzotriazole and their ability to form chalcogen bonds
Mirgaux, M., Scaillet, T., Kozlova, A., Tumanov, N., Frédérick, R., Bodart, L. & Wouters, J., 1 Apr 2022, In: Acta Crystallographica. Section E: Crystallographic Communications. 78, 4, p. 418-424 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile32 Downloads (Pure) -
Temporary Intermediates of L-Trp Along the Reaction Pathway of human Indoleamine 2,3-dioxygenase 1 and Identification of an Exo Site
Mirgaux, M., Leherte, L. & Wouters, J., 15 Dec 2021, In: International Journal of Tryptophan Research. 14, p. 1- 11Research output: Contribution to journal › Article › peer-review
Open AccessFile45 Downloads (Pure) -
Influence of the presence of the heme cofactor on the JK-loop structure in indoleamine-2,3-dioxygenase-1
Mirgaux, M., Leherte, L. & Wouters, J., 1 Dec 2020, In: Acta crystallographica. Section D: Structural Biology. 76, p. 1211-1221Research output: Contribution to journal › Article › peer-review
Open AccessFile40 Downloads (Pure)
Datasets
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Crystal structure of L-Trp/Indoleamine 2,3-dioxygenase (hIDO1) complex with the JK-loop refined in the intermediate conformation
MIRGAUX, M. (Creator) & Wouters, J. (Creator), University of Namur, 29 Dec 2021
DOI: 10.2210/pdb7P0R/pdb
Dataset
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PSPH Human phosphoserine phosphatase
Wouters, J. (Creator), Haufroid, M. (Creator) & MIRGAUX, M. (Creator), University of Namur, 12 Jun 2019
DOI: 10.2210/pdb6HYJ/pdb
Dataset
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Structure of human indoleamine-2,3-dioxygenase 1 (hIDO1) with a complete JK loop
MIRGAUX, M. (Creator) & Wouters, J. (Creator), University of Namur, 16 Dec 2020
DOI: 10.2210/pdb7A62/pdb
Dataset
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Crystal structure of L-Trp/Indoleamine 2,3-dioxygenagse 1 (hIDO1) complex with the JK-loop refined in the closed conformation
MIRGAUX, M. (Creator) & Wouters, J. (Creator), University of Namur, 29 Dec 2021
DOI: 10.2210/pdb7NGE/pdb
Dataset
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Human phosphoserine phosphatase with substrate analogue homo-cysteic acid
Wouters, J. (Creator), Haufroid, M. (Creator) & MIRGAUX, M. (Creator), University of Namur, 12 Jun 2019
DOI: 10.2210/pdb6Q6J/pdb
Dataset
Prizes
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Mechanistic study of the human phosphoserine phosphatase (hPSP): crystallographic and computational approaches
MIRGAUX, M. (Recipient), 15 Nov 2019
Prize: Prize (including medals and awards)
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Mechanistic study of the human phosphoserine phosphatase (hPSP): crystallographic and computational approaches
MIRGAUX, M. (Recipient), 10 Oct 2019
Prize: Prize (including medals and awards)
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Young Medicinal Chemist Award in Belgium (SRC)
MIRGAUX, M. (Recipient), 19 May 2022
Prize: Prize (including medals and awards)
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9th EFMC Young Medicinal Chemists' Symposium
MIRGAUX, M. (Contributor)
9 Sept 2022Activity: Participating in or organising an event types › Participation in conference
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33rd European Crystallography Meeting
MIRGAUX, M. (Poster)
23 Aug 2022 → 27 Aug 2022Activity: Participating in or organising an event types › Participation in conference
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3rd FNRS Med Chem Symposium
MIRGAUX, M. (Contributor)
19 May 2022Activity: Participating in or organising an event types › Participation in conference
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Women and Girls in Science
MIRGAUX, M. (Poster)
27 Apr 2022 → 28 Apr 2022Activity: Participating in or organising an event types › Participation in conference
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Journée-Rencontre des Jeunes Chimistes
MIRGAUX, M. (Contributor)
1 Apr 2022Activity: Participating in or organising an event types › Participation in conference
Thesis
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Étude mécanistique de la phosphosérine phosphatase humaine, une enzyme impliquée dans la chimiorésistance au 5-Fluorouracile dans le cancer du côlon : approches expérimentale et computationnelle
Mirgaux, M. (Author), Wouters, J. (Supervisor) & Champagne, B. (Co-Supervisor), Jun 2019Student thesis: Master types › Master in Chemistry Research focus
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Plasticity of human indoleamine-2,3-dioxygenases 1 and 2 through a structural approach combining crystallography and Molecular Dynamics studies
MIRGAUX, M. (Author), Wouters, J. (Supervisor), Olivier, Y. (President), Leherte, L. (Jury), Labar, G. (Jury), Röhrig, U. (Jury) & Wintjens, R. (Jury), 16 Nov 2022Student thesis: Doc types › Doctor of Sciences
File