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2019

Assessment of second and third generation oral contraceptives APC resistance by a newly validated ETP-based APC resistance assay: a pilot study

Morimont, L., Evrard, J., Delvigne, A-S., Bouvy, C., Dogné, J-M. & Douxfils, J., Nov 2019, BSTH, 27th annual meeting, Program and Abstracts book, 28-29 november, 2019. p. 20 P04

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Assessment of thrombomodulin resistance in women using second generation, third generation and progestin-only contraceptives

Morimont, L., Evrard, J., Delvigne, A-S., Bouvy, C., Dogné, J-M. & Douxfils, J., Nov 2019, BSTH, 27th annual meeting, Program and Abstracts book, 28-29 november, 2019. p. 20 P05

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Comparison of the impact of DOACs on hemostasis diagnostic tests

Siriez, R., Evrard, J., Dogne, J-M., Mullier, F. & Douxfils, J., 2019, Comparison of the impact of DOACs on hemostasis diagnostic tests.

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Investigation of Cyclic Ligand Inhibiting CD2-CD58 Interactions Using Molecular Dynamics and Molecular Docking Approaches - COMP579

Vercauteren, D., Leherte, L., Laurent, A. & Jacquemin, D., Apr 2019, Abstracts of the 2557th Annual Meeting and Exposition of the American Chemical Society.

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Proposition of a new scale for the harmonization and normalization of the nAPCsr: a scientific and regulatory need for clinical studies comparison

Morimont, L., Evrard, J., Delvigne, A-S., Bouvy, C., Dogné, J-M. & Douxfils, J., Nov 2019, BSTH, 27th annual meeting, Program and Abstracts book, 28-29 november, 2019. p. 20-21 P07

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Validation of an original ETP-based APC resistance assay for the evaluation of prothrombotic states

Morimont, L., Evrard, J., Delvigne, A-S., Bouvy, C., Dogné, J-M. & Douxfils, J., Nov 2019, BSTH, 27th annual meeting, Program and Abstracts book, 28-29 november, 2019. p. 20 P06

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

2018

Betrixaban: Impact on routine and specific coagulation assays - A practical laboratory guide

Siriez, R., Evrard, J., Dogne, J-M., Pochet, L., Gheldof, D., Chatelain, B., Vancraeynest, C., Devel, P., Guldenpfennig, M., Devroye, C., Mullier, F. & Douxfils, J., 5 Jul 2018, JTH - Journal of thrombosis and haemostasis: Research and Practice in thrombosis and haemostasis. Issue S1 ed. Vol. Volume 2. PB364

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Betrixaban : Impact on routine and specific coagulation assays - A practical laboratory guide

Siriez, R., Evrard, J., Dogne, J-M., Pochet, L., Gheldof, D., Chatelain, B., Vancraeynest, C., Devel, P., Guldenpfennig, M., Devroye, C., Mullier, F. & Douxfils, J., 2018, BJH - Belgian Journal of Hematology - Clinic: Abstracts - 33rd General Annual Meeting of the Belgian Hematology Society . p. 22 42 p. PP47

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Betrixaban: Impact on routine and specific coagulation assays - Practical laboratory guidance

Siriez, R., Evrard, J., Dogne, J-M., Pochet, L., Gheldof, D., Chatelain, B., Vancraeynest, C., Devel, P., Guldenpfennig, M., Devroye, C., Mullier, F. & Douxfils, J., 2018, International Society for Laboratory Hematology: Abstracts.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Clot waveform analysis: Determination of optimal wavelength to assess the fibrin coagulation process

Evrard, J., Siriez, R., Bouvy, C., Laloy, J., Mullier, F., Dogne, J-M. & Douxfils, J., 5 Jul 2018, JTH-Journal of Thrombosis and haemostasis: Research and practice of thrombosis and haemostasis. issue S1 ed. Vol. 2. PB385

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Clot waveform analysis for measuring and quantifying fibrin clot formation

Evrard, J., Siriez, R., Themans, P., Laloy, J., Mullier, F., Dogne, J-M. & Douxfils, J., 5 Jul 2018, JTH - Journal of thrombosis and haemostasis: Research and pratice in thrombosis and haemostasis. issue S1 ed. Vol. 2. PB582

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Influence of Protein-Solvent Interactions on the Molecular Dynamics of Reduced Point Charge Models of Proteins - COMP5

Leherte, L. & Vercauteren, D., 2018, Abstracts of the 255th Annual Meeting and Exposition of the American Chemical Society. ACS

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Intrinsic Flexibility of the μ Opioid Receptor through Multiscale Modelling Approaches - COMP403

Vercauteren, D., Fossepre, M., Leherte, L. & Laaksonen, A., 2018, Abstracts of the 255th Annual Meeting and Exposition of the American Chemical Society. ACS

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In Vitro Effects of BCR-ABL Tyrosine Kinase Inhibitors on Endothelial Cells Survival and Functions

Haguet, H., Douxfils, J., Chatelain, C., GRAUX, C., Mullier, F. & Dogne, J-M., 5 Jul 2018, Special Issue: Abstracts of the 64th Annual Meeting of the Scientific Standardization Committee of the International Society on Thrombosis and Haemostasis, July 18–21, 2018. p. 242 1 p. PB497. (Research and Practice in Thrombosis and Haemostasis; vol. 2, no. S1).

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2017

A New Method for Determining Concentrations of Direct Oral Anticoagulants

Bloemen, S., Zwaveling, S., Douxfils, J., Peters, T., Wagenvoord, R., Hemker, H. C., Mullier, F., de Laat, B., Roest, M. & Kremers, R., 2017, Research and practice in thrombosis and haemostasis: Abstracts of the XXVI Congress of the International Society on Thrombosis and Haemostasis, July 8–13, 2017. Vol. 1. p. 968 1 p.

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Circulating microRNAs as biomarkers in diffuse large B-cell lymphoma: a pilot prospective longitudinal clinical study

Bouvy, C., Wannez, A., Chatelain, C. & Dogne, J-M., May 2017, 22nd Congress Of The European Hematology Association Madrid, Spain, June 22–25, 2017.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Efficacy of a Novel Contact Pathway Inhibitor, Ir-CPI, on in vitro Clotting Induced by PCI Catheter Segment

Douxfils, J., Gheldof, D., Derochette, S., Tassignon, J., Meinguet, C., Guyaux, M., Dogne, J-M. & Godfroid, E., 2017, Research and practice in thrombosis and haemostasis: Abstracts of the XXVI Congress of the International Society on Thrombosis and Haemostasis, July 8–13, 2017. Vol. 1. p. 1044-1045 2 p.

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Open Access
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Heparin Calibrated Anti-Xa Assays for the Measurement of Low Levels of Direct Factor Xa Inhibitors

Sabor, L., Raphaël, M., Dogne, J-M., Mullier, F. & Douxfils, J., 2017, Research and practice in thrombosis and haemostasis: Abstracts of the XXVI Congress of the International Society on Thrombosis and Haemostasis, July 8–13, 2017. Vol. 1. p. 1044 1 p.

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Impact of BCR-ABL Tyrosine Kinase Inhibitors on Atherosclerosis Plaque Rupture

Haguet, H., Douxfils, J., Chatelain, C. J., Graux, C., Mullier, F. & Dogné, J-M., 2017, Abstract and Meeting Program of the 59th ASH Annual Meeting. Suppl 1 ed. Vol. 130. p. 1591-1591 1 p. (Blood).

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

In Vitro Effects of BCR-ABL Tyrosine Kinase Inhibitors on Endothelial Cells Survival and Functions

Haguet, H., Douxfils, J., Chatelain, C. J., Graux, C., Mullier, F. & Dogné, J-M., 2017, Abstract and Meeting Program of the 59th ASH Annual Meeting. Suppl 1 ed. Vol. 130. p. 1592-1592 1 p. (Blood).

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Measurement of Direct Oral Anticoagulants Levels in Patients Admitted for Bleeding Events: A Prospective Study

Sennesael, A-L., Larock, A-S., Douxfils, J., Dogne, J-M., Spinewine, A. & Mullier, F., 2017, Research and practice in thrombosis and haemostasis: Abstracts of the XXVI Congress of the International Society on Thrombosis and Haemostasis, July 8–13, 2017. p. 989 1 p.

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Patients on a Fixed Dose of DOAC: What Percentage is in the Therapeutic Window?

Hemker, H. C., Bloemen, S., Kremers, R., Kelchtermans, H., Douxfils, J., Mullier, F. & de Laat, B., 2017, Research and practice in thrombosis and haemostasis: Abstracts of the XXVI Congress of the International Society on Thrombosis and Haemostasis, July 8–13, 2017. Vol. 1. p. 986-987 2 p.

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Stability of TGA Parameters in Patients Treated with Anticoagulants Using the Fully Automated ST-Genesia System

Douxfils, J., Nicolas, J-B., Larock, A-S., Devalet, B., Vandermeeren, Y., Gérard, V., Guldenpfennig, M., De Fays, K., Baudar, J. & Mullier, F., 2017, Research and practice in thrombosis and haemostasis: Abstracts of the XXVI Congress of the International Society on Thrombosis and Haemostasis, July 8–13, 2017. Vol. 1. p. 513-514 2 p.

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Standardization and Automation of Thrombin Generation Assay: on the Way to the Clinical Lab

Douxfils, J., Baudar, J., Guldenpfennig, M., Chatelain, B., Nicolas, J-B. & Mullier, F., 2017, Research and practice in thrombosis and haemostasis: Abstracts of the XXVI Congress of the International Society on Thrombosis and Haemostasis, July 8–13, 2017. Vol. 1. p. 507 1 p.

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The Impact of the Eculizumab on the Thrombogenicity Induced by Extracellular Vesicles in Paroxysmal Nocturnal Hemoglobinuria Patients

Wannez, A., Devalet, B., Bouvy, C., Bihin, B., Douxfils, J., Dogne, J-M. & Mullier, F., 2017, Research and practice in thrombosis and haemostasis: Abstracts of the XXVI Congress of the International Society on Thrombosis and Haemostasis, July 8–13, 2017. Vol. 1. p. 1083 1 p.

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2016

Application of a clot based assay to measure the procoagulant activity of stored allogeneic red blood cell concentrates

Devalet, B., Wannez, A., Bailly, N., Alpan, L., Gheldof, D., Douxfils, J., Deneys, V., Bihin, B., Chatelain, B., Dogne, J-M., Chatelain, C. & Mullier, F., 13 May 2016, Abstracts of the 62nd Annual Meeting of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis May 25–28, 2016. p. 142 1 p. VAS26

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Open Access

Estimation of rivaroxaban plasma concentrations in the perioperative setting with or without heparin bridging: an ex vivo study using dedicated chromogenic assays

Lessire, S., Douxfils, J., Pochet, L., Dincq, A-S., Larock, A-S., Gourdin, M., Dogné, J-M., Chatelain, B. & Mullier, F., 13 May 2016, Abstracts of the 62nd Annual Meeting of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis May 25–28, 2016. p. 21 1 p. CA30

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Open Access

L’expérience d’une collaboration fructueuse et pérenne entre la Belgique et la Tunisie dans le district minier de Nefza-Sejnane

Yans, J., Ben Abdallah, R., Decree, S., Chargui, H., Dekoninck, A., Moussi, B., Dupuis, C., Chaftar, H-R., Vandeneede, V., Hajjaji, W., Pilate, P., HATIRA, N., Baele, J. M., Wouters, J. & Jamoussi, F., 7 Apr 2016, Ressources and Innovative Geology 2016 - Abstract book.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Transfer of Multidrug Resistance Among Acute Myeloid Leukemia Cells Via Extracellular Vesicles and Their Micrornas Cargo

Bouvy, C., Wannez, A., Chatelain, C. & Dogne, J-M., 1 Dec 2016, 58th ASH Annual Meeting: Annual Meeting Abstracts. Blood ed. Vol. 128.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

2015

A DRVVT-based assay to estimate the intensity of anticoagulation in patients treated with NOACS

Sennesael, A-L., Douxfils, J., Exner, T., Larock, A-S., Dogné, J-M., Spinewine, A. & Mullier, F., 2015, J Thromb Haemost. 2015 Jun;13 Suppl 2:1-997. doi: 10.1111/jth.12993.: Abstracts of the XXV Congress of the International Society on Thrombosis and Haemostasis, June 20-25, 2015.. p. 798 1 p. PO125-WED

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C. canimorsus affects coagulation by proteolytic cleavage of factor X

Hack, K., Douxfils, J., Dogné, J-M. & Cornelis, G., 2015, J Thromb Haemost. 2015 Jun;13 Suppl 2:1-997. doi: 10.1111/jth.12993.: Abstracts of the XXV Congress of the International Society on Thrombosis and Haemostasis, June 20-25, 2015.. p. 616 1 p. PO299-TUE

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

2014

Estimation of dabigatran plasma concentrations in the perioperative setting. An ex-vivo study using dedicated coagulation assays.

Douxfils, J., Lessire, S., Dincq, A-S., Gourdin, M., Baudar, J., Chatelain, B., Dogne, J-M. & Mullier, F., 2014, Blood - 2014 ASH Annual Meeting Abstracts. Vol. 124.

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Fragment Expansion of 2,5-Dichlorophenyl to Discover New FXIIa Inhibitors

Bouckaert, C., Serra, S., Frédérick, R. & Pochet, L., 2014, Chemmedchem EFMC-ISMC 2014 Book of Abstracts. p. 229

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Interest of thrombin time in the periprocedural management for patients on dabigatran etexilate

Douxfils, J., Remacle, S., Lessire, S., Dincq, A-S., Gourdin, M., Chatelain, B., Dogne, J-M. & Mullier, F., 2014, Journal of Thrombosis and Haemostasis. 2014 Jun;12 Suppl 1:1-117.

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INTEREST OF THROMBIN TIME IN THE PERI-PROCEDURAL MANAGEMENT FOR PATIENTS ON DABIGATRAN ETEXILATE

Remacle, S., Lessire, S., Douxfils, J., Dincq, A-S., Gourdin, M., Chatelain, B., Dogne, J-M. & Mullier, F., 2014, INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY. Vol. 36. p. 95-95

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Thiosemicarbazide Derivatives as Novel Indolamine-2,3-dioxygenase (IDO) Inhibitors

Serra, S., Moineaux, L., Vancraeynest, C., Masereel, B., Pochet, L., Wouters, J. & Frédérick, R., 2014, Chemmedchem EFMC-ISMC 2014 Book of Abstracts. p. 280

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

What is the best time sampling for the two direct oral anticoagulants (DOACs), dabigatran and rivaroxaban?

Douxfils, J., Baudar, J., Devalet, B., Samama, M. M., Chatelain, B., Dogne, J-M. & Mullier, F., 2014, Journal of Thrombosis and Haemostasis. 2014 Jun;12 Suppl 1:1-117.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

2013

A nationwide Belgian survey on the influence of the new oral anticoagulants dabigatran and rivaroxaban on commonly used coagulation assays

van Blerk, M., Bailleul, E., Chatelain, B., Demulder, A., Devreese, K., Douxfils, J., Jochmans, K., Mullier, F., Wijns, W. & Soumali, M., 2013, Journal of Thrombosis and Haemostasis. 2013 Jul;11 Suppl 2:1-1322.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Apixaban: Safety, usefulness and practical details of laboratory monitoring

Douxfils, J., Mullier, F., Classen, J-F., Baudar, J., Walbrecq, S., Chatelain, C., Chatelain, B. & Dogne, J-M., 2013, Journal of Thrombosis and Haemostasis. 2013 Jul;11 Suppl 2:1-1322.

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COMPARISON BETWEEN THE CS-2000I (-) AND THE STA-R EVOLUTION FOR THE QUANTITATIVE MEASUREMENT OF DABIGATRAN IN PATIENT'S PLASMA USING THE HEMOCLOT THROMBIN INHIBITOR

Frederic, S., Douxfils, J., Mullier, F., Eeckhoudt, S. & Chatelain, B., 2013, INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY. Vol. 35. p. 65-65

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Comparison of Biophen DiXaI®, Prothrombin Time With a Reference HPLC-MS/MS Method to Monitor Patients Receiving Rivaroxaban

Douxfils, J., Tamigniau, A., Classen, J-F., Baudar, J., Walbrecq, S., Chatelain, C., Chatelain, B., Wallemacq, P., Mullier, F. & Dogne, J-M., 2013, Journal of Thrombosis and Haemostasis. 2013 Jul;11 Suppl 2:1-1322.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Comparison of Calibrated Automated Thrombogram and chronometric or chromogenic assays for the monitoring of DOACs in patients with non-valvular atrial fibrillation.

Douxfils, J., Classen, J-F., Baudar, J., Walbrecq, S., Chatelain, C., Chatelain, B., Mullier, F. & Dogne, J-M., 2013, Journal of Thrombosis and Haemostasis. 2013 Jul;11 Suppl 2:1-1322.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Comparison of Hemoclot Thrombin Inhibitor® and activated partial thromboplastin time with a reference UPLC-MS/MS method to monitor patients receiving Dabigatran Etexilate

Douxfils, J., Dogne, J-M., Mullier, F., Chatelain, B., Rönquist-Nii, Y., Malmström, RI. E. & Hjemdahl, P., 2013, Journal of Thrombosis and Haemostasis. 2013 Jul;11 Suppl 2:1-1322.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Dabigatran Etexilate and Risk Of Myocardial Infarction, Major Bleeding and All-Cause Mortality: A Systematic Review and Meta-Analysis Of Randomized Controlled Trials

Douxfils, J., Buckinx, F., Mullier, F., Minet, V., Rabenda, V., Reginster, J-Y., Hainaut, P., Bruyère, O. & Dogne, J-M., 2013, Blood 2013 122:3633; published ahead of print December 6, 2013.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Design and synthesis of thiosemicarbazides as inhibitors of Arginase I, a therapeutic target for anticancer immunotherapy

Colette, C., Vancraeynest, C., Serra, S., Pochet, L. & Frédérick, R., 2013, 2013 Book of Abstracts, 27èmes Journées franco-belges de Pharmacochimie / 21èmes Conférences européennes du GP2A. p. 45

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Dilute Russell Viper Venom Time: A useful assay for the monitoring of direct oral anticoagulants in patients?

Douxfils, J., Vanhoutteghem, A., Classen, J-F., Baudar, J., Walbrecq, S., Chatelain, C., Chatelain, B., Dogne, J-M. & Mullier, F., 2013, Journal of Thrombosis and Haemostasis. 2013 Jul;11 Suppl 2:1-1322.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Duration of Anticoagulation in Venous Thromboembolism : a Retrospective Analysis of a Large Cohort in a Belgian Disease Registry

Douxfils, J., Pothen, L., Mullier, F., Dogne, J-M. & Hainaut, P., 2013, Abstracts of the 21th Annual Meeting of the Belgian Society on Thrombosis and Haemostasis.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Duration of anticoagulation in venous thromboembolism (VTE) : a retrospective analysis of a large Belgian cohort.

Hainaut, P., Douxfils, J., Pothen, L., Mullier, F. & Dogne, J-M., 2013, Acta Clinica Belgica. Vol. 68. p. 460-460

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Impact of apixaban on haemostasis diagnosis assays: Practical recommendations

Douxfils, J., Mullier, F., Classen, J-F., Baudar, J., Walbrecq, S., Chatelain, C., Chatelain, B. & Dogne, J-M., 2013, Journal of Thrombosis and Haemostasis. 2013 Jul;11 Suppl 2:1-1322.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Impact of CYP3A4*1G Polymorphism on plasmatic concentration profile of rivaroxaban (Xarelto) assessed by coagulation assays

Douxfils, J., Mullier, F., Chatelain, C., Chatelain, B. & Dogne, J-M., 2013, Journal of Thrombosis and Haemostasis. 2013 Dec;11 Suppl 3:1-105.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution