Résumé
Evidence of the existence of two forms of cyclooxygenases and the clinical relevance of COX-2 inhibition led to the development of COX-2 selective NSAIDs. In order to evaluate this selectivity, we have developed and validated an enzymatic method. The precision and reproducibility of the assay were determined and COX-2 selectivity examined using nimesulide and indometacin.
langue originale | Anglais |
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Pages (de - à) | 89-90 |
Nombre de pages | 2 |
journal | Journal de Pharmacie de Belgique |
Volume | 54 |
Numéro de publication | 3 |
Etat de la publication | Publié - 1999 |