Résumé
Dermatophytosis is a superficial fungal infection of the keratinized structures of the host. Since the last decade, this mycosis became an important health concern due to an increasing prevalence and to the limited number and efficacy of available treatments. Several experimental models have then been developed in order to improve knowledge about this infection and to design new therapeutic strategies. This chapter presents the variety of dermatophytosis experimental models and their contribution in the understanding of mechanisms used by dermatophytes to adhere and to invade the host tissue. Their support to study the establishment of effective antifungal defenses by the host is also summarized. The usefulness of these models for testing the efficacy of antifungal compounds is finally discussed.
langue originale | Anglais |
---|---|
titre | Dermatophytes and Dermatophytoses |
rédacteurs en chef | Jean-Philippe Bouchara, Pietro Nenoff, Aditya K. Gupta, Vishnu Chaturvedi |
Lieu de publication | Cham, Switzerland |
Editeur | Springer |
Pages | 135-160 |
Nombre de pages | 26 |
ISBN (Electronique) | 978-3-030-67421-2 |
ISBN (imprimé) | 978-3-030-67420-5 |
Les DOIs | |
Etat de la publication | Publié - 8 juin 2021 |
Empreinte digitale
Examiner les sujets de recherche de « Experimental models of dermatophytosis ». Ensemble, ils forment une empreinte digitale unique.Thèses de l'étudiant
-
Pathogénie d’une dermatophytose (Trichophyton rubrum) sur épiderme humain reconstruit
Faway, É. (Auteur), Lambert De Rouvroit, C. (Copromoteur), Poumay, Y. (Promoteur), De Bolle, X. (Président), Del Marmol, V. (Jury), Jonca, N. (Jury), Mignon, B. (Jury) & Monod, M. (Jury), 7 mars 2018Student thesis: Doc types › Docteur en Sciences Biomédicales et Pharmaceutiques
Fichier