Experimental models of dermatophytosis

Émilie Faway, Marc Thiry, Bernard Mignon, Yves Poumay

Résultats de recherche: Contribution dans un livre/un catalogue/un rapport/dans les actes d'une conférenceChapitre (revu par des pairs)Revue par des pairs

Résumé

Dermatophytosis is a superficial fungal infection of the keratinized structures of the host. Since the last decade, this mycosis became an important health concern due to an increasing prevalence and to the limited number and efficacy of available treatments. Several experimental models have then been developed in order to improve knowledge about this infection and to design new therapeutic strategies. This chapter presents the variety of dermatophytosis experimental models and their contribution in the understanding of mechanisms used by dermatophytes to adhere and to invade the host tissue. Their support to study the establishment of effective antifungal defenses by the host is also summarized. The usefulness of these models for testing the efficacy of antifungal compounds is finally discussed.
langue originaleAnglais
titreDermatophytes and Dermatophytoses
rédacteurs en chefJean-Philippe Bouchara, Pietro Nenoff, Aditya K. Gupta, Vishnu Chaturvedi
Lieu de publicationCham, Switzerland
EditeurSpringer
Pages135-160
Nombre de pages26
ISBN (Electronique)978-3-030-67421-2
ISBN (imprimé)978-3-030-67420-5
Les DOIs
Etat de la publicationPublié - 2021

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