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Research Output 1984 2018

  • 2099 Citations
  • 20 h-Index
  • 70 Article
  • 2 Poster
  • 1 Comment/debate
2018

A microglial cell model for acyl-CoA oxidase 1 deficiency

Raas, Q., Saih, F-E., Gondcaille, C., Trompier, D., Hamon, Y., Leoni, V., Caccia, C., Nasser, B., Jadot, M., Ménétrier, F., Lizard, G., Cherkaoui-Malki, M., Andreoletti, P. & Savary, S., 2018, In : Biochimica et biophysica acta. Molecular and cell biology of lipids.

Research output: Contribution to journalArticle

Acyl-CoA Oxidase
Cell Line
Interleukin-6
Fatty Acids
Clustered Regularly Interspaced Short Palindromic Repeats
Open Access
File
Lipolysis
Autophagy
Adipocytes
Mitochondria
Triglycerides
2017

SNAT7 is the primary lysosomal glutamine exporter required for extracellular protein-dependent growth of cancer cells

Verdon, Q., Boonen, M., Ribes, C., Jadot, M., GASNIER, B. & Sagné, C., 2 May 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 18, p. E3602-E3611

Research output: Contribution to journalArticle

Neutral Amino Acid Transport Systems
Glutamine
Sodium
Growth
Neoplasms
2016

Accounting for protein subcellular localization: A compartmental map of the rat liver proteome

Jadot, M., Boonen, M., Thirion, J., Wang, N., Xing, J., Zhao, C., Tannous, A., Qian, M., Zheng, H., Everett, J. K., Moore, D. F., Sleat, D. E. & Lobel, P., 2016, In : Molecular & cellular proteomics : MCP.

Research output: Contribution to journalArticle

Open Access
File
Proteome
Liver
Rats
Organelles
Proteins
Golgi Apparatus
Endoplasmic Reticulum
Glycine
Autophagy
Yeast

Cathepsin D and its newly identified transport receptor SEZ6L2 can modulate neurite outgrowth

Boonen, M., Staudt, C., Gilis, F., Oorschot, V., Klumperman, J. & Jadot, M., 2016, In : Journal of Cell Science. 129, 3, p. 557-68 12 p.

Research output: Contribution to journalArticle

Cathepsin D
Endosomes
Uridine Diphosphate
Brain
Hydrolases
Golgi Apparatus
Endoplasmic Reticulum
Human Trafficking
trans-Golgi Network
Sequence Deletion

Microscopy: Access to the bigger picture in histology

Poumay, Y. & Jadot, M., 19 Mar 2015, In : Nature. 519, 7543, p. 291 1 p.

Research output: Contribution to journalComment/debate

The Na+/K+-ATPase and the amyloid-beta peptide aβ1-40 control the cellular distribution, abundance and activity of TRPC6 channels

Chauvet, S., Boonen, M., Chevallet, M., Jarvis, L., Abebe, A., Benharouga, M., Faller, P., Jadot, M. & Bouron, A., 1 Nov 2015, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1853, 11, p. 2957-2965 9 p., 17657.

Research output: Contribution to journalArticle

Amyloid beta-Peptides
Ouabain
Zinc Acetate
Veratridine
Biotinylation
2014
Lysosomes
Liver
Hyaluronic Acid
Hyaluronoglucosaminidase
Glycoside Hydrolases
Open Access
File
Brucella melitensis
Brucella abortus
Autophagy
Fibroblasts
Brucella
Macrophages
Hydrolases
Endosomes
Hyaluronic Acid
Protein Renaturation
2013
Open Access
File
Sterols
Sterol Regulatory Element Binding Proteins
Sucrose
Carrier Proteins
mevalonate kinase

An extended proteome map of the lysosomal membrane reveals novel potential transporters

Chapel, A., Kieffer-Jaquinod, S., Sagné, C., Verdon, Q., Ivaldi, C., Mellal, M., Thirion, J., Jadot, M., Bruley, C., Garin, J., Gasnier, B. & Journet, A., 1 Jun 2013, In : Molecular and Cellular Proteomics. 12, 6, p. 1572-1588 17 p.

Research output: Contribution to journalArticle

Proteome
Lysosomes
Membranes
Proteins
Proteomics
Open Access
File
Ceroid
Oxidative stress
Fibroblasts
Neuronal Ceroid-Lipofuscinoses
Oxidative Stress
2012

Lipids and lysosomes

Hamer, I., Van Beersel, G., Arnould, T. & Jadot, M., 1 Dec 2012, In : Current Drug and Metabolism. 13, 10, p. 1371-1387 17 p.

Research output: Contribution to journalArticle

Lysosomes
Lipids
Membranes
Macromolecules
Lysosomal Storage Diseases
2011

Classification of subcellular location by comparative proteomic analysis of native and density-shifted lysosomes

Della Valle, M. C., Sleat, D. E., Zheng, H., Moore, D. F., Jadot, M. & Lobel, P., 1 Apr 2011, In : Molecular and Cellular Proteomics. 10, 4

Research output: Contribution to journalArticle

Lysosomes
Proteomics
Proteins
Centrifugation
Organelles

Hyal2 is a glycosylphosphatidylinositol-anchored, lipid raft-associated hyaluronidase

Andre, B., Duterme, C., Van Moer, K., Mertens-Strijthagen, J., Jadot, M. & Flamion, B., 22 Jul 2011, In : Biochemical and Biophysical Research Communications. 411, 1, p. 175-179 5 p.

Research output: Contribution to journalArticle

Glycosylphosphatidylinositols
Hyaluronoglucosaminidase
Lipids
Membranes
Hyaluronic Acid

Loss of niemann-pick C1 or C2 protein results in similar biochemical changes suggesting that these proteins function in a common lysosomal pathway

Dixit, S. S., Jadot, M., Sohar, I., Sleat, D. E., Stock, A. M. & Lobel, P., 24 Aug 2011, In : PLoS ONE. 6, 8

Research output: Contribution to journalArticle

lysosomes
cholesterol
Lysosomes
Type C Niemann-Pick Disease
Proteins
2010

Endocytosis of hyaluronidase-1 by the liver

Gasingirwa, M-C., Thirion, J., Mertens-Strijthagen, J., Wattiaux-De Coninck, S., Flamion, B., Wattiaux, R. & Jadot, M., 1 Sep 2010, In : Biochemical journal. 430, 2, p. 305-313 9 p.

Research output: Contribution to journalArticle

Hyaluronoglucosaminidase
Endocytosis
Liver
Centrifugation
Enzymes
Ceroid
Neuronal Ceroid-Lipofuscinoses
Lysosomal Storage Diseases
Glial Fibrillary Acidic Protein
Lysosomes
2009
Cathepsin B
Osteosarcoma
Mitochondrial DNA
Up-Regulation
Oxidative Phosphorylation
2008

Acid phosphatase 5 is responsible for removing the mannose 6-phosphate recognition marker from lysosomal proteins

Sun, P., Sleat, D. E., Lecocq, M., Hayman, A. R., Jadot, M. & Lobel, P., 28 Oct 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 43, p. 16590-16595 6 p.

Research output: Contribution to journalArticle

Acid Phosphatase
Lysosomes
P-Glycoproteins
Enzymes
Neuroblastoma
Open Access
File
Lysosome-Associated Membrane Glycoproteins
Lysosomes
trans-Golgi Network
Sorting
Leucine

A method to assess the lysosomal residence of proteins in cultured cells

Gasingirwa, M. C., Thirion, J., Costa, C., Flamion, B., Lobel, P. & Jadot, M., 1 Mar 2008, In : Analytical biochemistry. 374, 1, p. 31-40 10 p.

Research output: Contribution to journalArticle

Lysosomes
Progesterone
Cultured Cells
Cells
Lysosome-Associated Membrane Glycoproteins
2007

Biochemical characterization and lysosomal localization of the mannose-6-phosphate protein p76 (hypothetical protein LOC196463)

Jensen, A. G., Chemali, M., Chapel, A., Kieffer-Jaquinod, S., Jadot, M., Garin, J. & Journet, A., 15 Mar 2007, In : Biochemical journal. 402, 3, p. 449-458 10 p.

Research output: Contribution to journalArticle

Proteins
Proteomics
Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase
IGF Type 2 Receptor
Protein Databases

Endocytosis provides a major alternative pathway for lysosomal biogenesis in kidney proximal tubular cells

Nielsen, R., Courtoy, P. J., Jacobsen, C., Dom, G., Lima, W. R., Jadot, M., Willnow, T. E., Devuyst, O. & Christensen, E. I., 27 Mar 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 13, p. 5407-5412 6 p.

Research output: Contribution to journalArticle

Low Density Lipoprotein Receptor-Related Protein-2
Cathepsin B
Endocytosis
Kidney
Lysosomes

Lysosomal proteomics and disease

Sleat, D. E., Jadot, M. & Lobel, P., 1 Sep 2007, In : Proteomics - Clinical Applications. 1, 9, p. 1134-1146 13 p.

Research output: Contribution to journalArticle

Proteomics
Organelles
Lysosomes
Macromolecular Substances
Inborn Genetic Diseases

Lysosomes and Fas-mediated liver cell death

Wattiaux, R., Wattiaux-De Coninck, S., Thirion, J., Gasingirwa, M. C. & Jadot, M., 1 Apr 2007, In : Biochemical journal. 403, 1, p. 89-95 7 p.

Research output: Contribution to journalArticle

Cell death
Lysosomes
Liver
Sulfites
Oxidoreductases Acting on Sulfur Group Donors
2006

Demonstration of lysosomal localization for the mammalian ependymin-related protein using classical approaches combined with a novel density shift method

Della Valle, M. C., Sleat, D. E., Sohar, I., Wen, T., Pintar, J. E., Jadot, M. & Lobel, P., 17 Nov 2006, In : Journal of Biological Chemistry. 281, 46, p. 35436-35445 10 p.

Research output: Contribution to journalArticle

Demonstrations
Lysosomes
Proteins
Proteomics
Lysosome-Associated Membrane Glycoproteins

Intracellular localization of p40, a protein identified in a preparation of lysosomal membranes

Boonen, M., Hamer, I., Boussac, M., Delsaute, A. F., Flamion, B., Garin, J. & Jadot, M., 1 Apr 2006, In : Biochemical journal. 395, 1, p. 39-47 9 p.

Research output: Contribution to journalArticle

Membranes
Lysosomes
Proteins
Lysosome-Associated Membrane Glycoproteins
Centrifugation
2005

Endolysosomal transport of newly-synthesized cathepsin D in a sucrose model of lysosomal storage

Hamer, I. & Jadot, M., 1 Oct 2005, In : Experimental Cell Research. 309, 2, p. 284-295 12 p.

Research output: Contribution to journalArticle

Cathepsin D
Organelles
Sucrose
Hydrolases
Lysosomes
2004

Calcium entry into keratinocytes induces exocytosis of lysosomes

Jans, R., Sartor, M., Jadot, M. & Poumay, Y., 1 Jun 2004, In : Archives of Dermatological Research. 296, 1, p. 30-41 12 p.

Research output: Contribution to journalArticle

Open Access
File
Ionomycin
Exocytosis
Lysosomes
Keratinocytes
Calcium
Keratinocytes
Up-Regulation
Chemical activation
Cholesterol
Epidermal Growth Factor Receptor
Hydrodynamics
Transfection
Hepatocytes
Injections
Liver
2003
Cathepsin C
Giardia lamblia
Trophozoites
Acid Phosphatase
Organelles

Uptake by mouse liver and intracellular fate of plasmid DNA after a rapid tail vein injection of a small or a large volume

Lecocq, M., Andrianaivo, F., Warnier, M. T., Wattiaux-De Coninck, S., Wattiaux, R. & Jadot, M., 1 Feb 2003, In : Journal of Gene Medicine. 5, 2, p. 142-156 15 p.

Research output: Contribution to journalArticle

Tail
Veins
Plasmids
Injections
Liver
2002

Importance of the propeptide in the biosynthetic maturation of rat cathepsin C

Santilman, V., Jadot, M. & Mainferme, F., 1 Dec 2002, In : European journal of cell biology. 81, 12, p. 654-663 10 p.

Research output: Contribution to journalArticle

Cathepsin C
Glycosylation
Enzymes
Lysosomes
Tryptophan

Uptake and intracellular fate of gelonin, a ribosome-inactivating protein, in rat liver

Colaço, M., Bapat, M. M., Misquith, S., Jadot, M., Wattiaux-De Coninck, S. & Wattiaux, R., 14 Oct 2002, In : Biochemical and Biophysical Research Communications. 296, 5, p. 1180-1185 6 p.

Research output: Contribution to journalArticle

Ribosome Inactivating Proteins
Liver
Rats
Radioactivity
Acids
2001

Effects of methylcyclodextrin on lysosomes

Jadot, M., Andrianaivo, F., Dubois, F. & Wattiaux, R., 2 Apr 2001, In : European Journal of Biochemistry . 268, 5, p. 1392-1399 8 p.

Research output: Contribution to journalArticle

Cyclodextrins
Lysosomes
Membranes
Centrifugation
Sucrose
2000

Endosomes, lysosomes: Their implication in gene transfer

Wattiaux, R., Laurent, N., Wattiaux-De Coninck, S. & Jadot, M., 30 Mar 2000, In : Advanced Drug Delivery Reviews. 41, 2, p. 201-208 8 p.

Research output: Contribution to journalArticle

Endosomes
Lysosomes
DNA
Plasmids
Genes

Identification of HE1 as the second gene of Niemann-Pick C disease

Naureckiene, S., Sleat, D. E., Lacklan, H., Fensom, A., Vanier, M. T., Wattiaux, R., Jadot, M. & Lobel, P., 22 Dec 2000, In : Science. 290, 5500, p. 2298-2301 4 p.

Research output: Contribution to journalArticle

Niemann-Pick Diseases
Fibroblasts
Genes
Lysosomes
Recombinant Proteins
Polyethyleneimine
Radioactivity
Lysosomes
Centrifugation
Polyamines
1999
Ceroid
Neuronal Ceroid-Lipofuscinoses
Enzyme Assays
Assays
Animals

Subcellular localization of mannose 6-phosphate glycoproteins in rat brain

Jadot, M., Lin, L., Sleat, D. E., Sohar, I., Hsu, M. S., Pintar, J., Dubois, F., Wattiaux-de Coninck, S., Wattiaux, R. & Lobel, P., 23 Jul 1999, In : Journal of Biological Chemistry. 274, 30, p. 21104-21113 10 p.

Research output: Contribution to journalArticle

Rats
Brain
Glycoproteins
Lysosomes
Enzymes

Uptake by rat liver and intracellular fate of plasmid DNA complexed with poly-L-lysine or poly-D-lysine

Laurent, N., Wattiaux-De Coninck, S., Mihaylova, E., Leontieva, E., Warnier-Pirotte, M. T., Wattiaux, R. & Jadot, M., 22 Jan 1999, In : FEBS Letters. 443, 1, p. 61-65 5 p.

Research output: Contribution to journalArticle

Liver
Lysine
Rats
Plasmids
DNA
1998

Expression of Lamp-1 and Lamp-2 and their interactions with galectin-3 in human tumor cells

Sarafian, V., Jadot, M., Foidart, J. M., Letesson, J-J., Van den Brule, F., Castrunovo, V., Wattiaux, R. & Wattiaux-De Coninck, S., 5 Jan 1998, In : International Journal of Cancer. 75, 1, p. 105-111 7 p.

Research output: Contribution to journalArticle

Lysosome-Associated Membrane Glycoproteins
Galactosides
Lectins
Neoplasms
Glycoproteins