Modifications de surfaces de Phynox
: vers une meilleure hydrophilicité et résistance à la corrosion dans une perspective d’applications biomédicales

Student thesis: Doc typesDoctor of Sciences


This thesis focuses on surface modification of Phynox substrate ; a Co and Cr based alloy. Phynox, by its numerous properties (amagnetic, resistant to corrosion, biocompatible), is a commonly used material in the biomedical applications (stents, needles, orthodontics, ...).
The aim of this thesis is to maximize the hydrophilicity of Phynox surfaces in order to improve its anti-thrombogenic character while also increasing its corrosion resistance.
To achieve these objectives, the development of hydrophilic layers using different techniques will be studied : the surface-initiated atom transfer radical polymerization (SI-ATRP), the development of polyelectrolytes layers (LbL) and the electrografting of diazonium salts.
Different characterization techniques will be used to assess the quality of the various developed hydrophilic coatings : X-ray photoelectron spectroscopy (XPS), the measurement of water static contact angle, ellipsometry, cyclic voltammetry (CV), linear sweep voltammetry (LSV) and attenuated total reflection infrared spectroscopy (ATR). Nuclear magnetic resonance (RMN) and thin-layer chromatography (CCM) will be used to check the efficiency of various organic synthesis carried out in this work.
Finally, all of this research has enabled the development hydrophilic layers, while improving corrosion resistance of a Phynox substrate.
Date of Award13 Mar 2015
Original languageFrench
Awarding Institution
  • University of Namur
SupervisorZineb MEKHALIF (Supervisor), Joseph DELHALLE (President), Catherine Michaux (Jury), Laetitia Mespouille (Jury) & Mohamed Mehdi Chehimi (Jury)

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