Terbogrel, a mixed thromboxane A2 receptor antagonist and thromboxane A2 synthase inhibitor, shows a hair-pin like conformation stabilized by an intramolecular hydrogen bond. A structural feature characteristic of the thromboxane A2 synthase inhibitor mode is observed. The structural properties of the compound are studied to understand the dual mode of action. H atoms were located in difference Fourier maps and then refined.
|Number of pages||2|
|Journal||Acta crystallographica Section C: Crystal Structure communications|
|Publication status||Published - 1 Oct 2000|