Is Thrombin Time useful for the assessment of dabigatran concentrations? An in vitro and ex vivo study

Sarah Lessire, Jonathan Douxfils, Justine Baudar, Nicolas Bailly, Anne Sophie Dincq, Maximilien Gourdin, Jean Michel Dogné, Bernard Chatelain, François Mullier

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)693-696
Number of pages4
JournalThrombosis Research
Issue number3
Publication statusPublished - 1 Sep 2015


  • Abbreviations HTI Hemoclot Thombin Inhibitors®
  • CV% Coefficient of variation expressed in percentage
  • ECA Ecarin chromogenic assay
  • LOD Limit of detection
  • LOQ Limit of quantification
  • NIH/ml National Institutes of Health (NIH) units per ml
  • NPP Normal pool plasma
  • OTC Optimal thrombin concentration
  • PPP Platelet-poor-plasma
  • SD Standard deviation
  • T<inf>MAX</inf> Limit of measurement of thrombin time
  • TT Thrombin time
  • UFH Unfractionated heparin

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