Cancer immunotherapy and dual IDO/TDO inhibitors: design, synthesis, physico-chemical and biological characterizations

Mirgaux, Manon (PI)
Wouters, Johan (Supervisor)

Project: Research

Short title	Dual TDO/IDO inhibition
Status	Finished
Effective start/end date	1/10/19 → 30/09/21

2 Article

Temporary Intermediates of L-Trp Along the Reaction Pathway of human Indoleamine 2,3-dioxygenase 1 and Identification of an Exo Site
Mirgaux, M., Leherte, L. & Wouters, J., 15 Dec 2021, In: International Journal of Tryptophan Research. 14, p. 1- 11
Research output: Contribution to journal › Article › peer-review

Open Access
File
31 Downloads (Pure)
Influence of the presence of the heme cofactor on the JK-loop structure in indoleamine-2,3-dioxygenase-1
Mirgaux, M., Leherte, L. & Wouters, J., 1 Dec 2020, In: Acta crystallographica. Section D: Structural Biology. 76, p. 1211-1221
Research output: Contribution to journal › Article › peer-review

Open Access
File
29 Downloads (Pure)

6 Participation in conference
1 Participation in workshop, seminar, course

11th Belgian Crystallography Symposium (BCS-11)
Manon MIRGAUX (Contributor)
17 Mar 2021
Activity: Participating in or organising an event types › Participation in conference
Journées Jeunes Chercheurs 2021 de la Société de Chimie thérapeutique
Manon MIRGAUX (Contributor)
11 Feb 2021 → 12 Feb 2021
Activity: Participating in or organising an event types › Participation in conference
Workshop RéNaFoBiS (Réseau National de Formation en Biologie Structurale Intégrative)
Manon MIRGAUX (Participant)
9 Oct 2020 → 16 Oct 2020
Activity: Participating in or organising an event types › Participation in workshop, seminar, course

Structure of human indoleamine-2,3-dioxygenase 1 (hIDO1) with a complete JK loop
Mirgaux, M. (Creator) & Wouters, J. (Creator), University of Namur, 16 Dec 2020
DOI: 10.2210/pdb7A62/pdb
Dataset