Loco-Regional Adjuvant Radiotherapy in Breast Cancer
: Retrospective Analysis of the Toxicity and Impact of the COVID-19 Pandemic

  • Julinne Stokart

Student thesis: Master typesMaster en sciences biomédicales à finalité spécialisée en recherche clinique

Résumé

Radiotherapy for breast cancer has evolved over the past few years. Initially, radiotherapy for patients with early breast cancer was performed by delivering a total dose of 50 Gy, i.e., 25 fractions of 2.0 Gy. Gradually, different treatment schedules were developed offering shorter schedules with lower total doses. According to the current ESTRO-ACROP recommendations, the standard of care is the 15-fraction START schedule which can be used regardless of the area to be irradiated. But the occurrence of COVID-19 pandemic has prompted Ste-Elisabeth hospital to treat all nodepositive breast cancer patients over 65 years of age with a shorter 5-fraction FAST schedule, i.e., one fraction per week for five weeks, based on French retrospective data and long experience. However, currently, FAST-Forward ultrahypofractionation with 5-fraction radiotherapy (one fraction per day) is still not recommended in the axillary area for safety reasons and the FAST schedule is not mentioned.
la date de réponse17 janv. 2023
langue originaleAnglais
L'institution diplômante
  • Universite de Namur
SuperviseurVincent M. Remouchamps (Promoteur) & Anne-Emmanuella Yeo (Copromoteur)

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