TY - JOUR
T1 - Toxicological impact of environmental microplastics and benzo[a]pyrene in the seaworm Hediste diversicolor under environmentally relevant exposure conditions
AU - Abouda, Siwar
AU - Missawi, Omayma
AU - Cappello, Tiziana
AU - Boughattas, Iteb
AU - De Marco, Giuseppe
AU - Maisano, Maria
AU - Banni, Mohamed
N1 - Funding Information:
This research was supported by funds from the Tunisian Ministry of Higher Education, Research Unit ( LR21AGR02 ) and the ENICBC-Med project COMMON (contract number: A_B.4.4_080 ).
Publisher Copyright:
© 2022 Elsevier Ltd
PY - 2022/10/1
Y1 - 2022/10/1
N2 - Nowadays, marine ecosystems are under severe threat from the simultaneous presence of multiple stressors, including microplastics (MPs) and polycyclic aromatic hydrocarbons (PAHs) such as benzo[a]pyrene (B[a]P). In addition to their presence in various marine compartments, there are increasing concerns on the potential capacity of MPs to sorb, concentrate and transfer these pollutants in the environment. Although their ecotoxicological impacts are currently evident, few works have studied the combined effects of these contaminants. Therefore, the major purpose of this work was to assess the toxicity of environmental relevant concentrations of MPs (<30 μm) and B[a]P, alone and in mixture, in the seaworm Hediste diversicolor by exploring their accumulation and hazardous biological effects for 3 and 7 days. Environmental MPs were able to increase B[a]P in a time-dependent manner. The obtained results showed that individual treatments, as well as co-exposure to contaminants, caused cytotoxicity and genotoxicity in the cœlomic fluid cells, while oxidative stress effects were observed at tissue and gene levels associated with alteration in neurotransmission. Overall, our findings provide additional clues about MPs as organic pollutant vectors in the marine environment, and contribute to a clearer understanding of their toxicological risk to aquatic invertebrates.
AB - Nowadays, marine ecosystems are under severe threat from the simultaneous presence of multiple stressors, including microplastics (MPs) and polycyclic aromatic hydrocarbons (PAHs) such as benzo[a]pyrene (B[a]P). In addition to their presence in various marine compartments, there are increasing concerns on the potential capacity of MPs to sorb, concentrate and transfer these pollutants in the environment. Although their ecotoxicological impacts are currently evident, few works have studied the combined effects of these contaminants. Therefore, the major purpose of this work was to assess the toxicity of environmental relevant concentrations of MPs (<30 μm) and B[a]P, alone and in mixture, in the seaworm Hediste diversicolor by exploring their accumulation and hazardous biological effects for 3 and 7 days. Environmental MPs were able to increase B[a]P in a time-dependent manner. The obtained results showed that individual treatments, as well as co-exposure to contaminants, caused cytotoxicity and genotoxicity in the cœlomic fluid cells, while oxidative stress effects were observed at tissue and gene levels associated with alteration in neurotransmission. Overall, our findings provide additional clues about MPs as organic pollutant vectors in the marine environment, and contribute to a clearer understanding of their toxicological risk to aquatic invertebrates.
KW - Environmental MPs
KW - Polychaete
KW - Polycyclic aromatic hydrocarbons
KW - Toxicological response
KW - Trojan horse effect
UR - http://www.scopus.com/inward/record.url?scp=85135694613&partnerID=8YFLogxK
U2 - 10.1016/j.envpol.2022.119856
DO - 10.1016/j.envpol.2022.119856
M3 - Article
C2 - 35944779
AN - SCOPUS:85135694613
SN - 0269-7491
VL - 310
JO - Environmental Pollution
JF - Environmental Pollution
M1 - 119856
ER -