Résumé
Tandem Haller-Bauer-scission/Grob-fragmentation reaction of cyclopentanone bearing a leaving group in β-position involves antiperiplanar arrangements which can be also achieved from epimeric derivatives, probably due to the high flexibility of the five-membered ring. We have observed that epimeric compounds react at different rates if the leaving group is a halogen and leads to very different types of compounds when it is a mesyl group.
langue originale | Anglais |
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Pages (de - à) | 3045-3049 |
journal | Tetrahedron Letters |
Volume | 51 |
Numéro de publication | 23 |
Les DOIs | |
Etat de la publication | Publié - 9 juin 2010 |