Studies of cell signaling in a reconstructed human epidermis exposed to sensitizers: IL-8 synthesis and release depend on EGFR activation

Keyphrases

• Growth Factor Receptor Tyrosine Kinase 100%
• Mechanistic Approach 50%
• Tyrosine Kinase Activity 50%
• MAPK Activation 50%
• Topical Application 50%
• IL-8 mRNA 50%
• 2,4-dinitrofluorobenzene 50%
• Transient Activation 50%
• Tissue Exposure 50%
• Toxicological Screening 50%
• Contact Sensitization 50%
• Oxazolone 50%
• Isoeugenol 50%
• Transient Expression 50%
• Complex Response 50%
• Allergic Contact Dermatitis 50%
• Cytokine Factors 50%
• Cell Release 50%
• Cinnamaldehyde 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Oxazolone 62%
• Cinnamaldehyde 62%
• Isoeugenol 62%
• 1 Fluoro 2,4 Dinitrobenzene 62%
• Skin Allergy 62%

INIS

• tyrosine 83%
• dermatitis 41%