Recognition of β-ketoalcohol-derived haptens by tailor-made antibodies

A. Krief; J.-J. Letesson; D. Swinnen; D. Billen

Recognition of β-ketoalcohol-derived haptens by tailor-made antibodies

A. Krief, J.-J. Letesson, D. Swinnen, D. Billen

Research output: Contribution to journal › Article › peer-review

Abstract

Antibodies steamed from mice immunized towards three different conjugates do not recognize the β-ketoalcohol for which they have been elaborated. They however recognize the haptens, which bear the side chain linking them to the carrier proteins. We have synthesized and tested for recognition a series of compounds related to those haptens, especially stereoisomers and compounds bearing part of their structures. Results and hypotheses are presented below.

Original language	English
Pages (from-to)	931-936
Number of pages	6
Journal	Synlett
Issue number	SPEC. ISS
Publication status	Published - 1 Jan 2001

Cite this

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abstract = "Antibodies steamed from mice immunized towards three different conjugates do not recognize the β-ketoalcohol for which they have been elaborated. They however recognize the haptens, which bear the side chain linking them to the carrier proteins. We have synthesized and tested for recognition a series of compounds related to those haptens, especially stereoisomers and compounds bearing part of their structures. Results and hypotheses are presented below.",

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AB - Antibodies steamed from mice immunized towards three different conjugates do not recognize the β-ketoalcohol for which they have been elaborated. They however recognize the haptens, which bear the side chain linking them to the carrier proteins. We have synthesized and tested for recognition a series of compounds related to those haptens, especially stereoisomers and compounds bearing part of their structures. Results and hypotheses are presented below.

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Recognition of β-ketoalcohol-derived haptens by tailor-made antibodies

Abstract

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