Abstract
Photophysical properties of quinoxalin-2(1H)-ones have long been neglected, in particular compared with those of coumarins, their oxygenated counterparts, despite their complementarity in terms of absorbance and fluorescence windows. This review provides first an overview of the synthesis of quinoxalin-2(1H)-ones, focusing on the most recent contributions. Fluorescence properties of quinoxalin-2(1H)-ones and of their π-extended derivatives are tackled through the description of a series of examples and applications, including chemosensing and biosensing.
| Original language | English |
|---|---|
| Article number | e202201314 |
| Journal | European Journal of Organic Chemistry |
| Volume | 2022 |
| Issue number | 48 |
| DOIs | |
| Publication status | Published - 27 Dec 2022 |
Funding
We thank the Region Haute-Normandie (FEDER CHIMBIO HN0001401) for financial support to K. R. This work has also been partially supported by University of Rouen Normandy, the Centre National de la Recherche Scientifique (CNRS), INSA Rouen Normandy, European Regional Development Fund (ERDF), Labex SynOrg (ANR-11-LABX-0029), Carnot Institute I2C, the graduate school for research XL-Chem (ANR-18-EURE-0020XL CHEM). We also thank Karolina Weronika Świderska for proofreading the manuscript. We thank the Region Haute‐Normandie (FEDER CHIMBIO HN0001401 ) for financial support to K. R. This work has also been partially supported by University of Rouen Normandy, the Centre National de la Recherche Scientifique (CNRS), INSA Rouen Normandy, European Regional Development Fund (ERDF), Labex SynOrg (ANR‐11‐LABX‐0029), Carnot Institute I2C, the graduate school for research XL‐Chem (ANR‐18‐EURE‐0020XL CHEM). We also thank Karolina Weronika Świderska for proofreading the manuscript.
Keywords
- biological applications
- fluorescence
- imaging applications
- quinoxalin-2(1H)-one
- synthesis