Prediction of first hyperpolarizability of fluorescent proteins

Evelien De Meulenaere, Marc de Wergifosse, Edith Botek, Jos Vanderleyden, Benoit Champagne, Koen Clays

Research output: Contribution to journalArticle


In an attempt to investigate the predictability of nonlinear optical properties of fluorescent proteins, we have experimentally and theoretically determined the first hyperpolarizability of eGFP, eYFP, ZsYellow, DsRed, mStrawberry and mCherry. Our first comparisons between experiment and calculations meet our expectations and point out some key features, e.g. the strong dependence on x-ray data and sensitivity to environmental factors like pH and ionic strength.
Original languageEnglish
Pages (from-to)522
JournalAIP Conference Proceedings
Publication statusPublished - 2015

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