Gene expression silencing with 'specific' small interfering RNA goes beyond specificity: a study of key parameters to take into account in the onset of small interfering RNA off-target effects

Sebastien Vankoningsloo, Françoise De Longueville, Stephanie Evrard, Pierre Rahier, Andrée Houbion, Antoine Fattaccioli, Mélanie Piette Gastellier, José Remacle, Martine Raes, Patricia Renard, Thierry Arnould

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Biochemistry, Genetics and Molecular Biology