Abstract

Accurate assessment of the antibacterial activity of graphene requires consideration of both the graphene fabrication method and, for supported films, the properties of the substrate. Large-area graphene films produced by chemical vapor deposition were grown directly on copper substrates or transferred on a gold substrate and their effect on the viability and proliferation of the Gram-positive bacteria Staphylococcus aureus and the Gram-negative bacteria Escherichia coli were assessed. The viability and the proliferation of both bacterial species were not affected when they were grown on a graphene film entirely covering the gold substrate, indicating that conductivity plays no role on bacterial viability and graphene has no antibacterial activity against S. aureus and E. coli. On the other hand, antibacterial activity was observed when graphene coated the copper substrates, resulting from the release of bactericidal cupric ions in inverse proportion to the graphene surface coverage.

Original languageEnglish
Pages (from-to)310-316
Number of pages7
JournalCarbon
Volume84
Issue number1
DOIs
Publication statusPublished - 1 Jan 2015

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Graphite
Graphene
Chemical vapor deposition
Substrates
Gold
Escherichia coli
Copper
Bacteria
Ions
Fabrication

Cite this

@article{4471bbb8e29f45e8ac12c0368f712487,
title = "Do CVD grown graphene films have antibacterial activity on metallic substrates?",
abstract = "Accurate assessment of the antibacterial activity of graphene requires consideration of both the graphene fabrication method and, for supported films, the properties of the substrate. Large-area graphene films produced by chemical vapor deposition were grown directly on copper substrates or transferred on a gold substrate and their effect on the viability and proliferation of the Gram-positive bacteria Staphylococcus aureus and the Gram-negative bacteria Escherichia coli were assessed. The viability and the proliferation of both bacterial species were not affected when they were grown on a graphene film entirely covering the gold substrate, indicating that conductivity plays no role on bacterial viability and graphene has no antibacterial activity against S. aureus and E. coli. On the other hand, antibacterial activity was observed when graphene coated the copper substrates, resulting from the release of bactericidal cupric ions in inverse proportion to the graphene surface coverage.",
author = "L. Dellieu and E. Lawar{\'e}e and N. Reckinger and C. Didembourg and Letesson, {J. J.} and M. Sarrazin and O. Deparis and Matroule, {J. Y.} and Colomer, {J. F.}",
year = "2015",
month = "1",
day = "1",
doi = "10.1016/j.carbon.2014.12.025",
language = "English",
volume = "84",
pages = "310--316",
journal = "Carbon",
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TY - JOUR

T1 - Do CVD grown graphene films have antibacterial activity on metallic substrates?

AU - Dellieu, L.

AU - Lawarée, E.

AU - Reckinger, N.

AU - Didembourg, C.

AU - Letesson, J. J.

AU - Sarrazin, M.

AU - Deparis, O.

AU - Matroule, J. Y.

AU - Colomer, J. F.

PY - 2015/1/1

Y1 - 2015/1/1

N2 - Accurate assessment of the antibacterial activity of graphene requires consideration of both the graphene fabrication method and, for supported films, the properties of the substrate. Large-area graphene films produced by chemical vapor deposition were grown directly on copper substrates or transferred on a gold substrate and their effect on the viability and proliferation of the Gram-positive bacteria Staphylococcus aureus and the Gram-negative bacteria Escherichia coli were assessed. The viability and the proliferation of both bacterial species were not affected when they were grown on a graphene film entirely covering the gold substrate, indicating that conductivity plays no role on bacterial viability and graphene has no antibacterial activity against S. aureus and E. coli. On the other hand, antibacterial activity was observed when graphene coated the copper substrates, resulting from the release of bactericidal cupric ions in inverse proportion to the graphene surface coverage.

AB - Accurate assessment of the antibacterial activity of graphene requires consideration of both the graphene fabrication method and, for supported films, the properties of the substrate. Large-area graphene films produced by chemical vapor deposition were grown directly on copper substrates or transferred on a gold substrate and their effect on the viability and proliferation of the Gram-positive bacteria Staphylococcus aureus and the Gram-negative bacteria Escherichia coli were assessed. The viability and the proliferation of both bacterial species were not affected when they were grown on a graphene film entirely covering the gold substrate, indicating that conductivity plays no role on bacterial viability and graphene has no antibacterial activity against S. aureus and E. coli. On the other hand, antibacterial activity was observed when graphene coated the copper substrates, resulting from the release of bactericidal cupric ions in inverse proportion to the graphene surface coverage.

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U2 - 10.1016/j.carbon.2014.12.025

DO - 10.1016/j.carbon.2014.12.025

M3 - Article

VL - 84

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JF - Carbon

SN - 0008-6223

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