(Di)-aminoguanidine functionalization through transamination: An avenue to an auspicious class of supramolecular synthons

A.D. Naik, B. Tinant, Quoc Toan Le, J. Marchand-Brynaert, B.-L. Su, Y. Garcia

    Research output: Contribution to journalArticle

    Abstract

    N-4H-1,2,4-Triazol-4-yl-guanidine hydrochloride (L1) and a heterocyclized 3,4-diamino-4H-1,2,4-triazole hydrochloride (L2) were synthesized in good yields thanks to a transamination reaction of aminoguanidine and diaminoguanidine hydrochlorides, whose mechanism is presented. L1 and L2 crystallize in monoclinic (P2 /a) and triclinic (P1̄) space groups, respectively. Hydrogen bonding interactions dictated by H-donor, acceptor rich ligand framework together with lattice chloride ions in L1 and L2 organize the crystal packing into a three-dimensional (3D) supramolecular network. The crystal structure of L1 is the first one for a 1,2,4-triazole ligand constructed from aminoguanidine. Both L1 and L2 that exist in monocationic form were introduced as supramolecular synthons to prepare Zn(II) complexes. Scanning electron microscopy (SEM) images on a bulk sample of [Zn(L1) Cl ]Cl ·H O (1) reveals a spontaneous aggregation of porous balls of coccolith morphology with surface decorated sickle-shaped particles of ∼100 nm thickness, whereas a powder sample of [Zn(L2) Cl ]·H O (2) shows neat rectangular blocks of ∼470 nm thickness. Colorless crystals of 2 crystallize in a monoclinic space group (C2/c). Zn(II) ions bound chloride with NH6B⋯Cl(1) = 2.495(2) Å and N⋯H type bonding (N6⋯H3C3 = 2.743(2) Å; N2⋯H7N7 = 1.989(2) Å) affording a 3D supramolecular network. The degree of pyramidality, ∑N = 38°, observed at one of the terminal amines in L2 is still retained in 2, but "flipping" of orientation of attached protons due to directional H-bonding is observed too. Porosity partitioning by mercury porosimetry measurements on 1 and 2 reveals interparticular porosities between 7 and 15 μm. N and H gas adsorption capacities of 1 and 2 were measured by BET which shows no preference for N but a low irreversible H uptake of 3 cm /g.
    Original languageEnglish
    Pages (from-to)4034-4043
    Number of pages10
    JournalCrystal Growth and Design
    Volume11
    Issue number9
    DOIs
    Publication statusPublished - 7 Sep 2011

    Fingerprint Dive into the research topics of '(Di)-aminoguanidine functionalization through transamination: An avenue to an auspicious class of supramolecular synthons'. Together they form a unique fingerprint.

  • Datasets

    CCDC 824791: Experimental Crystal Structure Determination

    Garcia, Y. (Contributor), Leonard, A. (Contributor), Marchand-Brynaert, J. (Contributor), Naik, A. D. (Contributor), SU, B. L. (Contributor) & Tinant, B. (Contributor), Cambridge Crystallographic Data Centre, 1 Jan 2011

    Dataset

    CCDC 824793: Experimental Crystal Structure Determination

    Garcia, Y. (Contributor), Leonard, A. (Contributor), Marchand-Brynaert, J. (Contributor), Naik, A. D. (Contributor), SU, B. L. (Contributor) & Tinant, B. (Contributor), Cambridge Crystallographic Data Centre, 1 Jan 2011

    Dataset

    CCDC 824792: Experimental Crystal Structure Determination

    Garcia, Y. (Contributor), Leonard, A. (Contributor), Marchand-Brynaert, J. (Contributor), Naik, A. D. (Contributor), SU, B. L. (Contributor) & Tinant, B. (Contributor), Cambridge Crystallographic Data Centre, 1 Jan 2011

    Dataset

    Cite this