Behavioral effects of the neurotoxin -N-methylamino- L-alanine on the mangrove rivulus ( Kryptolebias marmoratus) larvae.

Alessandra Carion, Julie Hétru, Angèle Markey, Victoria Suarez-Ulloa, Frédéric Silvestre

Research output: Contribution to journalArticle

Abstract

Mangrove rivulus, Kryptolebias marmoratus, is a hermaphrodite fish capable of self-fertilization. This particularity allows to naturally produce highly homozygous and isogenic individuals. Despite the low genetic diversity, rivulus can live in extremely variable environments and adjust its phenotype accordingly. This species represents a unique opportunity to clearly distinguish the genetic and non-genetic factors implicated in adaptation and evolution, such as epigenetic mechanisms. It is thus a great model in aquatic ecotoxicology to investigate the effects of xenobiotics on the epigenome, and their potential long-term impacts. In the present study, we used the mangrove rivulus to investigate the effects of the neurotoxin b-N-methylamino-L-alanine (BMAA) on larvae behaviors after 7 days exposure to two sub-lethal concentrations. Results show that BMAA can affect the maximal speed and prey capture (trials and failures), suggesting potential impacts on the organism's fitness.

Original languageEnglish
Pages (from-to)7820
Number of pages3
JournalJournal of Xenobiotics
Volume8
Issue number1
DOIs
Publication statusPublished - 2018

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Neurotoxins
Alanine
Fish
Larva
Self-Fertilization
Ecotoxicology
Xenobiotics
Epigenomics
Fishes
Phenotype

Keywords

  • Behavior
  • Developmental origin of health and disease
  • L
  • Mangrove rivulus
  • N
  • Neurotoxin
  • alanine.
  • methylamino
  • β

Cite this

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title = "Behavioral effects of the neurotoxin -N-methylamino- L-alanine on the mangrove rivulus ( Kryptolebias marmoratus) larvae.",
abstract = "Mangrove rivulus, Kryptolebias marmoratus, is a hermaphrodite fish capable of self-fertilization. This particularity allows to naturally produce highly homozygous and isogenic individuals. Despite the low genetic diversity, rivulus can live in extremely variable environments and adjust its phenotype accordingly. This species represents a unique opportunity to clearly distinguish the genetic and non-genetic factors implicated in adaptation and evolution, such as epigenetic mechanisms. It is thus a great model in aquatic ecotoxicology to investigate the effects of xenobiotics on the epigenome, and their potential long-term impacts. In the present study, we used the mangrove rivulus to investigate the effects of the neurotoxin b-N-methylamino-L-alanine (BMAA) on larvae behaviors after 7 days exposure to two sub-lethal concentrations. Results show that BMAA can affect the maximal speed and prey capture (trials and failures), suggesting potential impacts on the organism's fitness.",
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Behavioral effects of the neurotoxin -N-methylamino- L-alanine on the mangrove rivulus ( Kryptolebias marmoratus) larvae. / Carion, Alessandra; Hétru, Julie; Markey, Angèle; Suarez-Ulloa, Victoria; Silvestre, Frédéric.

In: Journal of Xenobiotics, Vol. 8, No. 1, 2018, p. 7820.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Behavioral effects of the neurotoxin -N-methylamino- L-alanine on the mangrove rivulus ( Kryptolebias marmoratus) larvae.

AU - Carion, Alessandra

AU - Hétru, Julie

AU - Markey, Angèle

AU - Suarez-Ulloa, Victoria

AU - Silvestre, Frédéric

PY - 2018

Y1 - 2018

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