α-Methoxy-benzylmetals: Original synthesis and reactivity

A. Krief, J. Bousbaa

Research output: Contribution to journalArticle

Abstract

Although 1-methoxy-1-methylseleno-toluene is efficiently metallated by KDA, the same compound as well as its higher homologues react with t-butyllithium producing 1-methoxy benzyllithiums via the C-Se bond cleavage. These species are efficiently alkylated by alkyl halides, even the secondary ones and react with THF in the presence of BF-OEt to produce the homologated tetrahydropyran derivative in good yield.
Original languageEnglish
Pages (from-to)6289-6290
Number of pages2
JournalTetrahedron Letters
Volume38
Issue number35
DOIs
Publication statusPublished - 1 Sep 1997

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