Molecular modelling of the LCAT (Lecithin Cholesterol Acyl Transferase), enzyme associated to the reverse cholesterol transport

Project: Research

Project Details

Description

Once tranformed into mature HDL by the LCAT, nascent HDL present an anti-atherogenic effect. By different modeling techniques, we try to obtain a model of structure for the LCAT. This structural approach of the LCAT.
StatusFinished
Effective start/end date1/09/9431/12/99

Keywords

  • molecular structure
  • molecular modelling
  • scanning tunneling microscope
  • atherosclerosis
  • X-ray diffraction
  • cholesterol
  • triglycerides