Folding studies and characterization of membrane proteins.

Project: PHD

Project Details

Description

We analyze the factors governing the system of both a detergent (SDS) and a co-solvent of diol (MPD), recently demonstrated as efficient for the renaturation of proteins, using biochemical and biophysical methods. Obtained informations will be used to design effective methods of renaturation, in particular of membrane proteins (porins in beta-barrels of Brucella).
StatusFinished
Effective start/end date1/10/101/10/14

Research Output

  • Refolding of SDS-denatured proteins using amphipathic cosolvents and osmolytes

    Roussel, G., Tinti, E., Perpète, E. & Michaux, C., 3 Sep 2013, In : Current Protocols in Protein Science. 28.5, SUPPL.72, p. 1 - 9 9 p., 28.5.

    Research output: Contribution to journalArticle

  • Activities

    • 8 Participation in conference

    CECAM workshop Simulation of bimolecular interactions with inorganic and organic surfaces as a challenge for future nanotechnologies

    Guillaume Roussel (Contributor)

    24 Mar 201426 Mar 2014

    Activity: Participating in or organising an event typesParticipation in conference

    Structure et Fonction des Macromolécules Biologiques, Bioinformatique, et Modélisation

    Guillaume Roussel (Poster)

    15 Nov 2013

    Activity: Participating in or organising an event typesParticipation in conference

    Frontiers in dynamics simulations of biological molecules

    Guillaume Roussel (Poster)

    4 Nov 20136 Nov 2013

    Activity: Participating in or organising an event typesParticipation in conference