Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of Pharmacy, Deciphering the pathways that lead to IDO1 constitutive expression in human cancer cells, UCLouvain
Award Date: 19 Dec 2017
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Collaborations and top research areas from the last five years
Projects
- 1 Active
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Harnessing the metabolic switch that occurs in early pancreatic cancer events for therapy and detection
Hennequart, M. (PI)
1/01/25 → 31/12/28
Project: Research
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Cycling back to folate metabolism in cancer
Younghwan, L., Vousden, K. H. & Hennequart, M., 2 May 2024, In: Nature Cancer. 5, 5, p. 701-715 15 p.Research output: Contribution to journal › Review article › peer-review
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ALDH1L2 regulation of formate, formyl-methionine, and ROS controls cancer cell migration and metastasis
Hennequart, M., Pilley, S. E., Labuschagne, C. F., Coomes, J., Mervant, L., Driscoll, P. C., Legrave, N. M., Lee, Y., Kreuzaler, P., Macintyre, B., Panina, Y., Blagih, J., Stevenson, D., Strathdee, D., Schneider-Luftman, D., Grönroos, E., Cheung, E. C., Yuneva, M., Swanton, C. & Vousden, K. H., 27 Jun 2023, In: Cell Reports. 42, 6, 112562.Research output: Contribution to journal › Article › peer-review
Open AccessFile15 Downloads (Pure) -
Loss of attachment promotes proline accumulation and excretion in cancer cells
Pilley, S. E., Hennequart, M., Vandekeere, A., Blagih, J., Legrave, N. M., Fendt, S. M., Vousden, K. H. & Labuschagne, C. F., 8 Sept 2023, In: Science Advances. 9, 36, p. eadh2023 eadh2023.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Downloads (Pure) -
The dietary sweetener sucralose is a negative modulator of T cell-mediated responses
Zani, F., Blagih, J., Gruber, T., Buck, M. D., Jones, N., Hennequart, M., Newell, C. L., Pilley, S. E., Soro-Barrio, P., Kelly, G., Legrave, N. M., Cheung, E. C., Gilmore, I. S., Gould, A. P., Garcia-Caceres, C. & Vousden, K. H., 23 Mar 2023, In: Nature. 615, 7953, p. 705-711 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile30 Downloads (Pure) -
Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy
Tajan, M., Hennequart, M., Cheung, E. C., Zani, F., Hock, A. K., Legrave, N., Maddocks, O. D. K., Ridgway, R. A., Athineos, D., Suárez-Bonnet, A., Ludwig, R. L., Novellasdemunt, L., Angelis, N., Li, V. S. W., Vlachogiannis, G., Valeri, N., Mainolfi, N., Suri, V., Friedman, A. & Manfredi, M. & 3 others, , 1 Dec 2021, In: Nature Communications. 12, 1, 366.Research output: Contribution to journal › Article › peer-review
Open AccessFile31 Downloads (Pure)
Press/Media
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Francis Crick Institute Reports Findings in Cancer (ALDH1L2 regulation of formate, formyl-methionine, and ROS controls cancer cell migration and metastasis)
14/06/23
1 item of Media coverage
Press/Media: Expert Comment
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New Study: Common Artificial Sweetener Has an “Unexpected Effect” on the Immune System
25/04/23
3 items of Media coverage
Press/Media: Expert Comment