Pharmacology, Toxicology and Pharmaceutical Science
Malignant Neoplasm
100%
Tryptophan 2,3 Dioxygenase
92%
Indole Derivative
65%
Tryptophan
65%
Indoleamine 2,3 Dioxygenase
62%
Immunotherapy
58%
Neoplasm
47%
Indoleamine 2,3 Dioxygenase Inhibitor
43%
Virtual Screening
41%
Enzyme
35%
Indole
34%
Immunomodulating Agent
30%
Indoleamine
15%
Phenyl Group
15%
Immunosuppressive Agent
15%
Quinolinic Acid
15%
Cupriavidus metallidurans
13%
Structure Activity Relationship
13%
Drug Development
13%
Kynurenine
12%
Liver Enzyme
11%
Bioavailability
10%
Systemic Treatment
8%
Biological Activity
7%
Mouse
6%
Drug Discovery
6%
IC50
6%
Cyanide
5%
Enzyme Inhibition
5%
Chemistry
Inhibitor
91%
Dioxygenases
74%
Synthesis (Chemical)
50%
Tryptophan
48%
Crystal Structure
37%
1H-Indole
34%
Compound Isomer
30%
Electronic Property
30%
Indole
26%
% Inhibition
23%
Group
19%
Kynurenine
16%
Dipole Moment
16%
Imidazole
15%
Heme Oxygenase
15%
Molecular Modeling
15%
Monoamine
15%
Crystal Phase Property
15%
Molecule
12%
Solubility
12%
Quantum Mechanics
12%
Binding Site
10%
X-Ray Diffraction
8%
Electrostatic Potential
8%
Quinolinic Acid
8%
Heterocyclic Compound
7%
Substitution Reaction
7%
Phenyl Group
7%
Inhibition Constant (Ki)
7%
Methyl Group
7%
Atom
7%
Bioactivity
7%
Procedure
7%
Reaction Mechanism
7%
Structure
6%
Single Crystalline Solid
6%
Heme
6%
Chemical Kinetics Characteristics
5%
Medicine and Dentistry
Tryptophan 2,3 Dioxygenase
46%
Enzyme
40%
Tryptophan
40%
Indole Derivative
35%
Cancer Cell
35%
Neoplasm
35%
Virtual Screening
30%
Comprehension
30%
Indoleamine 2,3 Dioxygenase
20%
Kynurenine
20%
Quinolinic Acid
20%
Cancer Therapy
17%
Immune System
17%
Immunosuppressive Treatment
17%
Immunotherapy
17%
Depletion
17%
Patient
17%
Immunosuppressive Drug
17%
Malignant Neoplasm
17%
Combination Therapy
17%
T Lymphocyte
17%
Cupriavidus metallidurans
14%
X Ray Diffraction
7%
Affinity Chromatography
5%