INIS
indoles
100%
cancer
98%
tryptophan
78%
immunotherapy
64%
synthesis
58%
tumors
38%
inhibition
36%
enzymes
34%
hydrogen 1
23%
isomers
21%
crystals
21%
design
21%
therapy
20%
modeling
20%
in vivo
16%
heme
16%
range
15%
crystal structure
13%
screening
13%
patients
11%
resist
11%
hydrogen 5
10%
oxygenases
10%
oxidases
10%
imidazoles
10%
optimization
10%
humans
9%
drugs
9%
in vitro
9%
kynurenine
8%
immunosuppression
8%
values
7%
chains
7%
solubility
7%
structure-activity relationships
6%
grants
6%
lymphocytes
6%
proliferation
6%
crystallography
5%
evaluation
5%
orientation
5%
aromatics
5%
kinetics
5%
methylation
5%
screens
5%
variations
5%
iron
5%
rings
5%
diseases
5%
Pharmacology, Toxicology and Pharmaceutical Science
Malignant Neoplasm
77%
Tryptophan 2,3 Dioxygenase
76%
Indoleamine 2,3 Dioxygenase
73%
Immunotherapy
60%
Indole Derivative
45%
Indole
43%
Neoplasm
37%
Indoleamine 2,3 Dioxygenase Inhibitor
34%
Tryptophan
32%
Immunomodulating Agent
21%
Structure Activity Relationship
19%
Kynurenine
18%
Virtual Screening
17%
Vaccination Policy
12%
Indoleamine
10%
Thiosemicarbazide
10%
Phenyl Group
10%
Competitive Inhibitor
10%
Amine Oxidase (Flavin Containing) Isoenzyme A
10%
Binding Site
10%
Methyl Group
10%
Amine Oxidase (Flavin Containing)
10%
Amine Oxidase (Flavin Containing) Isoenzyme B
10%
Immunosuppressive Agent
9%
Cupriavidus metallidurans
9%
Drug Development
8%
Quinolinic Acid
7%
Drug Discovery
6%
IC50
6%
Bond Length
5%
Molecular Target
5%
Keyphrases
1H-indole
23%
Indoleamine 2,3-dioxygenase 1 (IDO1)
23%
Crystalline Properties
21%
Pyridinyl
21%
Novel Inhibitors
21%
Tryptophan 2,3-dioxygenase (TDO2)
21%
Promising Target
21%
Ethanones
21%
Anticancer Immunotherapy
21%
Cancer Cells
20%
Cancer Therapy
19%
Indoleamine 2,3-dioxygenase Inhibitor
14%
Immune Rejection
12%
3-dioxygenase Inhibitor
12%
Tryptophan Depletion
10%
Natural Immune System
10%
Enzymatic Mechanism
10%
Efficacy in Vivo
10%
TDO Inhibitor
10%
Thiosemicarbazide
10%
Indolamine 2,3-dioxygenase
10%
Alkenyl
10%
Indole
10%
Structure Modeling
10%
Immunomodulator
10%
Chloro
10%
Electronic Properties
10%
Orally Active
10%
Immune Resistance
10%
Indol
10%
Tryptophan
9%
Cancer Tumor
9%
Quinolinic Acid
9%
Immunosuppression
9%
Tumor
9%
Therapeutic Vaccination
9%
Rapid Degradation
9%
Electrostatic Dipole
9%
Kynurenine Pathway
7%
T Cells
7%
Cancer Patients
7%
Coplanarity
7%
Cl Atoms
7%
Posters
7%
Virtual Screening
7%
Synthetic Inhibitors
5%
Molecular Electrostatic Potential
5%
4-phenylthiosemicarbazide
5%
Dipole Moment
5%
X Ray Diffraction
5%