The stochastic evolution of a protocell. The Gillespie algorithm in a dynamically varying volume.

Timoteo Carletti, Alessandro Filisetti

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Résumé

In the present paper we propose an improvement of the Gillespie algorithm allowing us to study the time evolution of an ensemble of chemical reactions occurring in a varying volume, whose growth is directly related to the amount of some specific molecules, belonging to the reactions set. This allows us to study the stochastic evolution of a protocell, whose volume increases because of the production of container molecules. Several protocells models are considered and compared with the deterministic models.
langue originaleAnglais
Pages (de - à)1-13
Nombre de pages13
journalComputational and Mathematical Methods in Medicine
Volume423627
Etat de la publicationPublié - 2012

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