Résumé
NFκB is a ubiquitous transcription factor involved in the proinflammatory response to cytokines (such as IL-1 or TNF-α) and some particular stresses. The unraveling of the molecular mechanisms involved in its activation is quite recent, particularly in the case of IL-1-stimulated cells, but the identification of the molecules involved in this pathway opens new prospects in both pharmacological and toxicological research.
langue originale | Anglais |
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Pages (de - à) | 341-344 |
Nombre de pages | 4 |
journal | Cell biology and toxicology |
Volume | 15 |
Numéro de publication | 6 |
Les DOIs | |
Etat de la publication | Publié - 1999 |