Résumé
We have developed a controlled-release drug carrier. Smartly controlled-release polymer nanoparticles were firstly synthesized through RAFT polymerization as the controlled-release core. The structural and particle properties of polymer nanoparticles were characterized by nuclear magnetic resonance spectroscopy (1H-NMR), scanning electron microscope (SEM) and X-ray spectroscopy (EDX). Mesoporous materials were selected as the shell materials to encapsulate the smart core as the stable shell. The mesoporous shell was characterized by transmission electron microscopy (TEM) and scanning electron microscope (SEM). All the results showed that a well-defined core-shell structure with mesoporous structure was obtained, and this controllable delivery system will have the great potential in nanomedicine.
langue originale | Anglais |
---|---|
Pages (de - à) | 658-664 |
Nombre de pages | 7 |
journal | Journal Wuhan University of Technology, Materials Science Edition |
Volume | 35 |
Numéro de publication | 3 |
Les DOIs | |
Etat de la publication | Publié - 1 juin 2020 |
Empreinte digitale
Examiner les sujets de recherche de « Synthesis of the Core-Shell Structure Materials as the Controlled-Release Drug Carrier ». Ensemble, ils forment une empreinte digitale unique.Équipement
-
Physico-chimie et caractérisation (PC2)
Johan Wouters (!!Manager) & Carmela Aprile (!!Manager)
Plateforme technologique Caracterisation physico-chimiquesEquipement/installations: Plateforme technolgique