Synthesis of D-glycero-D-manno-heptose 1,7-bisphosphate (HBP) featuring a β-stereoselective bis-phosphorylation

Résultats de recherche: Contribution à un journal/une revueArticle

Résumé

D-glycero-D-manno-Heptose 1,7-bisphosphate (HBP) plays a unique role in bacteriology. We describe in this study a very efficient synthesis of HBP, featuring a highly 6-D-selective construction of the heptose scaffold as well as a double phosphorylation step installing, in a single operation and in a β-stereoselective manner, the 1- and the 7-phosphates.

langueAnglais
Pages3631-3633
Nombre de pages3
journalTetrahedron Letters
Volume58
Numéro37
Les DOIs
étatPublié - 13 sept. 2017

Empreinte digitale

Bacteriology
Heptoses
Phosphorylation
Scaffolds
Phosphates
glycero-manno-heptose

mots-clés

    Citer ceci

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    title = "Synthesis of D-glycero-D-manno-heptose 1,7-bisphosphate (HBP) featuring a β-stereoselective bis-phosphorylation",
    abstract = "D-glycero-D-manno-Heptose 1,7-bisphosphate (HBP) plays a unique role in bacteriology. We describe in this study a very efficient synthesis of HBP, featuring a highly 6-D-selective construction of the heptose scaffold as well as a double phosphorylation step installing, in a single operation and in a β-stereoselective manner, the 1- and the 7-phosphates.",
    keywords = "Bacterial saccharides, Carbohydrates, Glycosidation, Phosphorylation",
    author = "Lina Liang and Vincent, {St{\'e}phane P.}",
    year = "2017",
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    journal = "Tetrahedron Letters",
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    Synthesis of D-glycero-D-manno-heptose 1,7-bisphosphate (HBP) featuring a β-stereoselective bis-phosphorylation. / Liang, Lina; Vincent, Stéphane P.

    Dans: Tetrahedron Letters, Vol 58, Numéro 37, 13.09.2017, p. 3631-3633.

    Résultats de recherche: Contribution à un journal/une revueArticle

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    KW - Bacterial saccharides

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