Structural characterization of oxidized lumiflavin hydrochloride hydrate: Comparison with the hydrogen bonding at the cofactor of flavoproteins

J. Wouters, F. Moureau, Ph Perpète, B. Norberg, G. Evrard, F. Durant

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Résumé

In order to examine the possibility of hydrogen bonding around the flavin ring, an X-ray diffraction study of the title compound was undertaken. Crystals of lumiflavin hydrochloride hydrate [2(C13H12N4O2) 4 HCl 7 H2O] are triclinic, space group {Mathematical expression}, Z=2, a=11.064(1), b=17.903(1), c=9.891(1)Å, α=111.9(6), β-96.4(8), γ=91.6(7)°. We present the crystal structure of this compound and compare it with other flavin derivatives and with the structure of the active site of some flavoproteins.

langue originaleAnglais
Pages (de - à)607-614
Nombre de pages8
journalJournal of chemical crystallography
Volume24
Numéro de publication9
Les DOIs
Etat de la publicationPublié - 1 sept. 1994

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