Structural approach of the mechanism of inhibition of α-chymotrypsin by coumarins

Johan Wouters; Marjorie Huygens; Lionel Pochet; Bernard Pirotte; François Durant; Bernard Masereel

doi:10.1016/S0960-894X(02)00073-2

Structural approach of the mechanism of inhibition of α-chymotrypsin by coumarins

Johan Wouters, Marjorie Huygens, Lionel Pochet, Bernard Pirotte, François Durant, Bernard Masereel

Unite de recherche en chimie physique, theorique et structurale

Résultats de recherche: Contribution à un journal/une revue › Article › Revue par des pairs

Résumé

A pharmacophore associated to the inhibiton of α-chymotrypsin has been built based on the structural and electronic characterization of a series of coumarin derivatives. © 2002 Elsevier Science Ltd. All rights reserved.

langue originale	Anglais
Pages (de - à)	1109-1112
Nombre de pages	4
journal	Bioorganic & Medicinal Chemistry Letters
Volume	12
Numéro de publication	7
Les DOIs	https://doi.org/10.1016/S0960-894X(02)00073-2
Etat de la publication	Publié - 8 avr. 2002

Accès au document

10.1016/S0960-894X(02)00073-2

Autres fichiers et liens

Link to publication in Scopus

13 Citations
1 Poster

STUDY OF COUMARINS WITH IMPROVED SOLUBILITY TO INHIBIT FXIIa, AN EMERGING TARGET IN THROMBOSIS RESEARCH
Bouckaert, C., Vancraeynest, C., Dolušić, E., Frédérick, R. & Pochet, L., 30 nov. 2012, p. Book of Abstracts, MedChem 2012, Château de Colonster, Liège - November 30, 2012, P01. 1 p.
Résultats de recherche: Contribution à un événement scientifique (non publié) › Poster

File

Physico-chimie et caractérisation (PC2)
Wouters, J. (!!Manager) & Aprile, C. (!!Manager)
Plateforme technologique Caracterisation physico-chimiques
Equipement/installations: Plateforme technolgique

Contient cette citation

@article{da15778d156c46e38c978d7a4a375a79,

title = "Structural approach of the mechanism of inhibition of α-chymotrypsin by coumarins",

abstract = "A pharmacophore associated to the inhibiton of α-chymotrypsin has been built based on the structural and electronic characterization of a series of coumarin derivatives. {\textcopyright} 2002 Elsevier Science Ltd. All rights reserved.",

author = "Johan Wouters and Marjorie Huygens and Lionel Pochet and Bernard Pirotte and Fran{\c c}ois Durant and Bernard Masereel",

year = "2002",

month = apr,

day = "8",

doi = "10.1016/S0960-894X(02)00073-2",

language = "English",

volume = "12",

pages = "1109--1112",

journal = "Bioorganic & Medicinal Chemistry Letters",

issn = "0960-894X",

publisher = "Elsevier",

number = "7",

}

TY - JOUR

T1 - Structural approach of the mechanism of inhibition of α-chymotrypsin by coumarins

AU - Wouters, Johan

AU - Huygens, Marjorie

AU - Pochet, Lionel

AU - Pirotte, Bernard

AU - Durant, François

AU - Masereel, Bernard

PY - 2002/4/8

Y1 - 2002/4/8

N2 - A pharmacophore associated to the inhibiton of α-chymotrypsin has been built based on the structural and electronic characterization of a series of coumarin derivatives. © 2002 Elsevier Science Ltd. All rights reserved.

AB - A pharmacophore associated to the inhibiton of α-chymotrypsin has been built based on the structural and electronic characterization of a series of coumarin derivatives. © 2002 Elsevier Science Ltd. All rights reserved.

UR - http://www.scopus.com/inward/record.url?scp=0037041189&partnerID=8YFLogxK

U2 - 10.1016/S0960-894X(02)00073-2

DO - 10.1016/S0960-894X(02)00073-2

M3 - Article

C2 - 11909728

SN - 0960-894X

VL - 12

SP - 1109

EP - 1112

JO - Bioorganic & Medicinal Chemistry Letters

JF - Bioorganic & Medicinal Chemistry Letters

IS - 7

ER -

Structural approach of the mechanism of inhibition of α-chymotrypsin by coumarins

Résumé

Accès au document

Autres fichiers et liens

Empreinte digitale

Résultat de recherche

STUDY OF COUMARINS WITH IMPROVED SOLUBILITY TO INHIBIT FXIIa, AN EMERGING TARGET IN THROMBOSIS RESEARCH

Équipement

Physico-chimie et caractérisation (PC2)

Contient cette citation