Structural approach of the mechanism of inhibition of α-chymotrypsin by coumarins

Johan Wouters; Marjorie Huygens; Lionel Pochet; Bernard Pirotte; François Durant; Bernard Masereel

doi:10.1016/S0960-894X(02)00073-2

Structural approach of the mechanism of inhibition of α-chymotrypsin by coumarins

Johan Wouters, Marjorie Huygens, Lionel Pochet, Bernard Pirotte, François Durant, Bernard Masereel

Unite de recherche en chimie physique, theorique et structurale

Résultats de recherche: Contribution à un journal/une revue › Article › Revue par des pairs

Résumé

A pharmacophore associated to the inhibiton of α-chymotrypsin has been built based on the structural and electronic characterization of a series of coumarin derivatives. © 2002 Elsevier Science Ltd. All rights reserved.

langue originale	Anglais
Pages (de - à)	1109-1112
Nombre de pages	4
journal	Bioorganic and medicinal chemistry letters
Volume	12
Numéro de publication	7
Les DOIs	https://doi.org/10.1016/S0960-894X(02)00073-2
Etat de la publication	Publié - 8 avr. 2002

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title = "Structural approach of the mechanism of inhibition of α-chymotrypsin by coumarins",

abstract = "A pharmacophore associated to the inhibiton of α-chymotrypsin has been built based on the structural and electronic characterization of a series of coumarin derivatives. {\textcopyright} 2002 Elsevier Science Ltd. All rights reserved.",

author = "Johan Wouters and Marjorie Huygens and Lionel Pochet and Bernard Pirotte and Fran{\c c}ois Durant and Bernard Masereel",

year = "2002",

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doi = "10.1016/S0960-894X(02)00073-2",

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Structural approach of the mechanism of inhibition of α-chymotrypsin by coumarins. / Wouters, Johan; Huygens, Marjorie; Pochet, Lionel; Pirotte, Bernard; Durant, François ; Masereel, Bernard.

Dans: Bioorganic and medicinal chemistry letters, Vol 12, Numéro 7, 08.04.2002, p. 1109-1112.

Résultats de recherche: Contribution à un journal/une revue › Article › Revue par des pairs

TY - JOUR

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AU - Wouters, Johan

AU - Huygens, Marjorie

AU - Pochet, Lionel

AU - Pirotte, Bernard

AU - Durant, François

AU - Masereel, Bernard

PY - 2002/4/8

Y1 - 2002/4/8

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JO - Bioorganic and medicinal chemistry letters

JF - Bioorganic and medicinal chemistry letters

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Structural approach of the mechanism of inhibition of α-chymotrypsin by coumarins

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