Space Radiobiology: Space Radiobiology

Christine Hellweg, Carmen Arena, Sarah Baatout, Bjorn Baselet, Kristina Beblo-Vranesevic, Nicol Caplin, Richard Coos, Fabiana Da Pieve, Veronica De Micco, Nicolas Foray, Boris Hespeels, Anne-Catherine Heuskin, Jessica Kronenberg, Tetyana Milojevic, Silvana Miranda, Victoria MORIS, Sebastien Penninckx, Wilhelmina Radstake, Emil Rehnberg, Petra RettbergKevin Tabury, Karine Van Doninck, Olivier Van Hoey, Guillaume Vogin, Yehoshua Socol

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Résumé

The study of the biologic effects of space radiation is considered a “hot topic,” with increased interest in the past years. In this chapter, the unique characteristics of the space radiation environment will be covered, from their history, characterization, and biological effects to the research that has been and is being conducted in the field. After a short introduction, you will learn the origin and characterization of the different types of space radiation and the use of mathematical models for the prediction of the radiation doses during different mission scenarios and estimate the biological risks due to this exposure. Following this, the acute, chronic, and late effects of radiation exposure in the human body are discussed before going into the detailed biomolecular changes affecting cells and tissues, and in which ways they differ from other types of radiation exposure. The next sections of this chapter are dedicated to the vast research that has been developed through the years concerning space radiation biology, from small animals to plant models and 3D cell cultures, the use of extremophiles in the study of radiation resistance mechanisms to the importance of ground-based irradiation facilities to simulate and study the space environment.

langue originaleAnglais
titreRadiobiology Textbook
rédacteurs en chefSarah Baatout
EditeurSpringer, Cham
Chapitre10
Pages503-569
Nombre de pages67
ISBN (Electronique)978-3-031-18810-7
ISBN (imprimé)978-3-031-18809-1
Les DOIs
Etat de la publicationPublié - 2023

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