Résumé
The regioselectivity of the ChxBCl/EtN-mediated (Chx = cyclohexyl) aldol reactions of ketones of general structure 2 has been studied and was shown to depend on both ketone structure and solvent. Useful levels of regioselectivity in favour of any of the two possible regioisomers were obtained in either pentane or diethyl ether. The relative configuration of the aldol products was assigned by H NMR studies of six-membered-ring derivatives. © Wiley-VCH Verlag GmbH & Co. KGaA, 2007.
langue originale | Anglais |
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Pages (de - à) | 4065-4075 |
Nombre de pages | 11 |
journal | European Journal of Organic Chemistry |
Volume | 2007 |
Numéro de publication | 24 |
Les DOIs | |
Etat de la publication | Publié - 1 janv. 2007 |