TY - JOUR
T1 - Sleep stabilizes visuomotor adaptation memory
T2 - a functional magnetic resonance imaging study
AU - Albouy, Genevieve
AU - Vandewalle, Gilles
AU - Sterpenich, Virginie
AU - Rauchs, Geraldine
AU - Desseilles, Martin
AU - Balteau, Evelyne
AU - Degueldre, Christian
AU - Phillips, Christophe
AU - Luxen, Andre
AU - Maquet, Pierre
N1 - © 2012 European Sleep Research Society.
PY - 2013/4
Y1 - 2013/4
N2 - The beneficial effect of sleep on motor memory consolidation is well known for motor sequence memory, but remains unsettled for visuomotor adaptation in humans. The aim of this study was to characterize more clearly the influence of sleep on consolidation of visuomotor adaptation using a between-subjects functional magnetic resonance imaging (fMRI) design contrasting sleep to total sleep deprivation. Our behavioural results, based on seven different parameters, show that sleep stabilizes performance whereas sleep deprivation deteriorates it. During training, while a set of cerebellar, striatal and cortical areas is activated in proportion to performance improvement, the recruitment of the hippocampus and frontal cortex protects motor memory against the detrimental effects of sleep deprivation. During retest after sleep loss a cerebello-cortical network, usually involved in the earliest stage of learning, was recruited to perform the task. In contrast, no changes in cerebral activity were observed after sleep, suggesting that it may only support the stabilization of the visuomotor adaptation memory trace.
AB - The beneficial effect of sleep on motor memory consolidation is well known for motor sequence memory, but remains unsettled for visuomotor adaptation in humans. The aim of this study was to characterize more clearly the influence of sleep on consolidation of visuomotor adaptation using a between-subjects functional magnetic resonance imaging (fMRI) design contrasting sleep to total sleep deprivation. Our behavioural results, based on seven different parameters, show that sleep stabilizes performance whereas sleep deprivation deteriorates it. During training, while a set of cerebellar, striatal and cortical areas is activated in proportion to performance improvement, the recruitment of the hippocampus and frontal cortex protects motor memory against the detrimental effects of sleep deprivation. During retest after sleep loss a cerebello-cortical network, usually involved in the earliest stage of learning, was recruited to perform the task. In contrast, no changes in cerebral activity were observed after sleep, suggesting that it may only support the stabilization of the visuomotor adaptation memory trace.
KW - Brain
KW - Female
KW - Functional Neuroimaging
KW - Humans
KW - Learning
KW - Magnetic Resonance Imaging
KW - Male
KW - Memory
KW - Psychomotor Performance
KW - Sleep
KW - Young Adult
U2 - 10.1111/j.1365-2869.2012.01059.x
DO - 10.1111/j.1365-2869.2012.01059.x
M3 - Article
C2 - 23121320
SN - 0962-1105
VL - 22
SP - 144
EP - 154
JO - Journal of sleep research
JF - Journal of sleep research
IS - 2
ER -