Single nucleotide polymorphism genotyping and distribution of Coxiella burnetii strains from field samples in Belgium

Fabiana Dal Pozzo, Bénédicte Renaville, Ludovic Martinelle, Robert Renaville, Christine Thys, François Smeets, Nathalie Kirschvink, Fabien Grégoire, Laurent Delooz, Guy Czaplicki, Claude Saegerman

Résultats de recherche: Contribution à un journal/une revueArticleRevue par des pairs

Résumé

The genotypic characterization of Coxiella burnetii provides useful information about the strains circulating at the farm, region, or country level and may be used to identify the source of infection for animals and humans. The aim of the present study was to investigate the strains of C. burnetii circulating in caprine and bovine Belgian farms using a single nucleotide polymorphism (SNP) technique. Direct genotyping was applied to different samples (bulk tank milk, individual milk, vaginal swab, fetal product, and air sample). Besides the well-known SNP genotypes, unreported ones were found in bovine and caprine samples, increasing the variability of the strains found in the two species in Belgium. Moreover, multiple genotypes were detected contemporarily in caprine farms at different years of sampling and by using different samples. Interestingly, certain SNP genotypes were detected in both bovine and caprine samples, raising the question of interspecies transmission of the pathogen.

langue originaleAnglais
Pages (de - à)81-86
Nombre de pages6
journalApplied and Environmental Microbiology
Volume82
Numéro de publication1
Les DOIs
Etat de la publicationPublié - 2016

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