@inproceedings{608036c331ea4f4da868b9d610e121b2,
title = "Regional wall motion analysis: An important tool to study pharmacologic agents in the absence of systemic effects",
abstract = "The value of a quantitative analysis of the regional systolic and diastolic function in analyzing the myocardial effects of drugs directly administered into coronary vessels was assessed in patients with aortic stenosis during an infusion of an ACE-inhibitor in the left main trunk. The computation of the changes in regional areas, of regional peak filling rate, of an index of regional chambcr stiffness and of the changes in regional area during tsovolumic relaxation revealed a selective improvement of myocardial diastolic function in the perfused territory. As this improvement remained undetected when the global indices of LV function were examined, it is concluded that regional wall motion analysis is indispensable to correctly assess the effects of intracoronary drug administration.",
author = "{Van Eyll}, C. and L. Stoleru and W. Hayashida and T. Bouvy and C. Hanet and {Van Mechelen}, H. and Charlier, {A. A.} and Rousseau, {M. F.} and H. Pouleur",
year = "1992",
month = jan,
day = "1",
doi = "10.1109/CIC.1992.269529",
language = "English",
series = "Proceedings - Computers in Cardiology, CIC 1992",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
pages = "527--530",
booktitle = "Proceedings - Computers in Cardiology, CIC 1992",
address = "United States",
note = "1992 IEEE Conference on Computers in Cardiology, CIC 1992 ; Conference date: 11-10-1992 Through 14-10-1992",
}