TY - JOUR
T1 - Recent advances of nucleotide nutrition research in aquaculture
T2 - a review
AU - Hossain, Md Sakhawat
AU - Koshio, Shunsuke
AU - Kestemont, Patrick
N1 - Publisher Copyright:
© 2019 Wiley Publishing Asia Pty Ltd
PY - 2020/5/1
Y1 - 2020/5/1
N2 - Although nucleotides (NT) have long been implicated as feed attractants in both vertebrate and invertebrate species, research into potential growth and health benefits of dietary NT in aquaculture species has just been implemented in early 2000s. To date, research pertaining to NT supplementation in aquafeed as functional nutrients has shown rather consistent and encouraging, beneficial results in fish and shrimp health management. Dietary NT serve a marked role to enhance growth in early stages of development, improve reproductive performances of brood fish, enhance larval quality, increase stress and disease resistance, modulate immune functions and improve intestinal morphology and gut microbiota of fish and shrimp. NT have also been used as functional supplement in alternative protein based diet, where NT was found as an effective supplement to increase the efficiency of utilizing alternative proteins. However, still there are numerous gaps in existing knowledge about exogenous NT administration to fish and shrimp including various aspects of digestion, absorption, metabolism, administration duration and age/size-related responses. Adoption of different molecular technologies, like proteome modification and study of several gene expression pattern related to growth, immunity, gut health and stress resistance in details are important for exploring the underlying mechanisms of NT functions in improved growth and health performances of fish and shrimp. Efforts are also needed on production technologies to reduce the NT cost. Moreover, extensive research information is also required regarding the use of NT in alternative protein and lipid based diet to develop cost-effective, ecofriendly functional aquafeed in near future.
AB - Although nucleotides (NT) have long been implicated as feed attractants in both vertebrate and invertebrate species, research into potential growth and health benefits of dietary NT in aquaculture species has just been implemented in early 2000s. To date, research pertaining to NT supplementation in aquafeed as functional nutrients has shown rather consistent and encouraging, beneficial results in fish and shrimp health management. Dietary NT serve a marked role to enhance growth in early stages of development, improve reproductive performances of brood fish, enhance larval quality, increase stress and disease resistance, modulate immune functions and improve intestinal morphology and gut microbiota of fish and shrimp. NT have also been used as functional supplement in alternative protein based diet, where NT was found as an effective supplement to increase the efficiency of utilizing alternative proteins. However, still there are numerous gaps in existing knowledge about exogenous NT administration to fish and shrimp including various aspects of digestion, absorption, metabolism, administration duration and age/size-related responses. Adoption of different molecular technologies, like proteome modification and study of several gene expression pattern related to growth, immunity, gut health and stress resistance in details are important for exploring the underlying mechanisms of NT functions in improved growth and health performances of fish and shrimp. Efforts are also needed on production technologies to reduce the NT cost. Moreover, extensive research information is also required regarding the use of NT in alternative protein and lipid based diet to develop cost-effective, ecofriendly functional aquafeed in near future.
KW - aquaculture
KW - fish performances
KW - functional nutrient
KW - immunonutrition
KW - immunostimulant
KW - nucleotide
UR - http://www.scopus.com/inward/record.url?scp=85075736120&partnerID=8YFLogxK
U2 - 10.1111/raq.12370
DO - 10.1111/raq.12370
M3 - Review article
AN - SCOPUS:85075736120
SN - 1753-5123
VL - 12
SP - 1028
EP - 1053
JO - Reviews in Aquaculture
JF - Reviews in Aquaculture
IS - 2
ER -