Pd-Co₃[Co(CN)₆]₂ hybrid nanoparticles: Preparation, characterization, and challenge for the Suzuki-Miyaura coupling of aryl chlorides under mild conditions

Because of their abundance and low cost, organo chlorides are the most desirable substrates from the industrial point of view in Suzuki-Miyaura cross-coupling reactions. However, catalytic application of Pd nanoparticles (NPs) for Suzuki coupling of aryl chlorides is still a challenge. Here, we design a novel catalyst by combining Pd NPs with Co₃[Co(CN)₆]₂ nanocrystals for Suzuki-Miyaura coupling of aryl chlorides. This nanocatalyst demonstrated good activity (yield 86.2% at 80 °C), high TOF, great stability, easy separation, excellent reusability (initial rates were not reduced after five cycles) and low cost in Suzuki reactions.