Résumé
cis-Chrysanthemic acid has been prepared in a few steps from dimethyldimedone via dibromination at alpha positions of each carbonyl carbons. The trans-dibromide which is almost exclusively formed has been isomerized to its cis-stereoisomer by highly chemoselective tandem H/K-K/H exchanges involving potassium bases at low temperature (
langue originale | Anglais |
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Pages (de - à) | 2398-2401 |
journal | Tetrahedron Letters |
Volume | 50 |
Numéro de publication | 20 |
Les DOIs | |
Etat de la publication | Publié - 20 mai 2009 |