TY - JOUR
T1 - Novel enantioselective syntheses of optically active (1R)-cis- and (1R)-trans-chrysanthemic acids
AU - Krief, A.
AU - Surleraux, D.
AU - Ropson, N.
PY - 1993/1/1
Y1 - 1993/1/1
N2 - Dimethyl dimedone, a non chiral and cheap compound, has been converted to the optically active 1-(R)-cis- and 1-(R)-trans-chrysanthemic acids possessing high economic value. These processes involve as the key steps (i) a cyclopropanation reaction (ii) a Grob fragmentation and (iii) a lipase monitored hydrolysis of the prochiral diacetate.
AB - Dimethyl dimedone, a non chiral and cheap compound, has been converted to the optically active 1-(R)-cis- and 1-(R)-trans-chrysanthemic acids possessing high economic value. These processes involve as the key steps (i) a cyclopropanation reaction (ii) a Grob fragmentation and (iii) a lipase monitored hydrolysis of the prochiral diacetate.
UR - http://www.scopus.com/inward/record.url?scp=0027483198&partnerID=8YFLogxK
U2 - 10.1016/S0957-4166(00)86070-X
DO - 10.1016/S0957-4166(00)86070-X
M3 - Article
AN - SCOPUS:0027483198
SN - 0957-4166
VL - 4
SP - 289
EP - 292
JO - Tetrahedron Asymmetry
JF - Tetrahedron Asymmetry
IS - 3
ER -