The DNA chips are arrays of DNA probes immobilized on solid support for silmutaneous indentification of many target DNA sequences. DNA chips applied to diagnosis aims to detect genomic DNA or RNA after PCR amplification. This review provides on overview of DNA chip technology, focusing on diagnostic applications. A comparison between high density and low density microarrays is given showing that low density chips are more suitable for routine applications due to their simplicity, good reproducibility, easy data management and low cost.
|titre||Biotechnology Annual Report|
|rédacteurs en chef||El Gewely|
|Nombre de pages||17|
|Etat de la publication||Publié - 2002|