New chips for molecular biology and diagnostics

Nathalie Zammatteo; Sandrine Hamels; Françoise De Longueville; Isabelle Alexandre; Jean-luc Gala; Francis Brasseur; José Remacle

New chips for molecular biology and diagnostics

Nathalie Zammatteo, Sandrine Hamels, Françoise De Longueville, Isabelle Alexandre, Jean-luc Gala, Francis Brasseur, José Remacle

Unite de recherche en biologie cellulaire animale

Résultats de recherche: Contribution dans un livre/un catalogue/un rapport/dans les actes d'une conférence › Chapitre

Résumé

The DNA chips are arrays of DNA probes immobilized on solid support for silmutaneous indentification of many target DNA sequences. DNA chips applied to diagnosis aims to detect genomic DNA or RNA after PCR amplification. This review provides on overview of DNA chip technology, focusing on diagnostic applications. A comparison between high density and low density microarrays is given showing that low density chips are more suitable for routine applications due to their simplicity, good reproducibility, easy data management and low cost.

langue originale	Anglais
titre	Biotechnology Annual Report
rédacteurs en chef	El Gewely
Pages	85-101
Nombre de pages	17
Volume	8
Etat de la publication	Publié - 2002

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title = "New chips for molecular biology and diagnostics",

abstract = "The DNA chips are arrays of DNA probes immobilized on solid support for silmutaneous indentification of many target DNA sequences. DNA chips applied to diagnosis aims to detect genomic DNA or RNA after PCR amplification. This review provides on overview of DNA chip technology, focusing on diagnostic applications. A comparison between high density and low density microarrays is given showing that low density chips are more suitable for routine applications due to their simplicity, good reproducibility, easy data management and low cost. ",

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author = "Nathalie Zammatteo and Sandrine Hamels and {De Longueville}, Fran{\c c}oise and Isabelle Alexandre and Jean-luc Gala and Francis Brasseur and Jos{\'e} Remacle",

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TY - CHAP

T1 - New chips for molecular biology and diagnostics

AU - Zammatteo, Nathalie

AU - Hamels, Sandrine

AU - De Longueville, Françoise

AU - Alexandre, Isabelle

AU - Gala, Jean-luc

AU - Brasseur, Francis

AU - Remacle, José

N1 - Publication editors : El Gewely, M.R.

PY - 2002

Y1 - 2002

N2 - The DNA chips are arrays of DNA probes immobilized on solid support for silmutaneous indentification of many target DNA sequences. DNA chips applied to diagnosis aims to detect genomic DNA or RNA after PCR amplification. This review provides on overview of DNA chip technology, focusing on diagnostic applications. A comparison between high density and low density microarrays is given showing that low density chips are more suitable for routine applications due to their simplicity, good reproducibility, easy data management and low cost.

AB - The DNA chips are arrays of DNA probes immobilized on solid support for silmutaneous indentification of many target DNA sequences. DNA chips applied to diagnosis aims to detect genomic DNA or RNA after PCR amplification. This review provides on overview of DNA chip technology, focusing on diagnostic applications. A comparison between high density and low density microarrays is given showing that low density chips are more suitable for routine applications due to their simplicity, good reproducibility, easy data management and low cost.

KW - DNA microarray

KW - diagnosis

M3 - Chapter

VL - 8

SP - 85

EP - 101

BT - Biotechnology Annual Report

A2 - Gewely, El

ER -

New chips for molecular biology and diagnostics

Résumé

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