MAGE-A4, a germ cell specific marker, is expressed differentially in testicular tumors

F Aubry, A P Satie, N Rioux-Leclercq, E Rajpert-De Meyts, G C Spagnoli, P Chomez, O De Backer, B Jégou, M Samson

Résultats de recherche: Contribution à un journal/une revueArticleRevue par des pairs

Résumé

Testicular germ cell tumors are the most common malignancy in young males, and the frequency of these tumors has risen dramatically over the last century. Because it is known that the MAGE genes are expressed in a wide variety of tumors but are expressed only in the mitotic spermatogonia (germ cells) and in the primary spermatocytes in the normal testis, the authors screened the expression of MAGE-A4 in a panel of testicular germ cell tumors.
langue originaleAnglais
Pages (de - à)2778-85
Nombre de pages8
journalCancer Research
Volume92
Numéro de publication11
Etat de la publicationPublié - 2001

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