In this work, we are the first to identify thirteen cocrystals of Nefiracetam, a poor water-soluble nootropic compound. Three of which were obtained with the biocompatible cocrystallization agents citric acid, oxalic acid, and zinc chloride. These latter have been fully structurally and physically characterized and the solubility, dissolution rate, and stability were compared to that of the initial Active Pharmaceutical Ingredient (API).
Empreinte digitaleExaminer les sujets de recherche de « Improving nefiracetam dissolution and solubility behavior using a cocrystallization approach ». Ensemble, ils forment une empreinte digitale unique.
Plateforme technologique Caracterisation physico-chimiques
Equipement/installations: Plateforme technolgique