Résumé
The identification and characterization of the inducible form of cyclooxygenases (COX-2) stimulated the investigations to develop efficient, non-steroidal anti-inflammatory drugs (NSAIDs) with reduced side effects (essentially gastro-intestinal toxicity) compared to classical NSAIDs. This review focuses on the chemical and pharmacological properties (pre-clinical data) of marketed COX-2 inhibitors.
langue originale | Anglais |
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Pages (de - à) | 597-601 |
Nombre de pages | 5 |
journal | Mini-reviews in medicinal chemistry |
Volume | 4 |
Numéro de publication | 6 |
Etat de la publication | Publié - août 2004 |